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NativeExtract™ Recombinant Full Length Human VDAC3 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW243)

This product is recombinant Human VDAC3 protein in native nanodisc form. The synthetic compound we developed can solubilize the VDAC3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • VDAC3
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 30.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • VDAC3
  • Full Name
  • Voltage Dependent Anion Channel 3
  • Introduction
  • This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene.
  • Alternative Names
  • Voltage Dependent Anion Channel 3; Outer Mitochondrial Membrane Protein Porin 3; VDAC-3; Voltage-Dependent Anion-Selective Channel Protein 3; HD-VDAC3; HVDAC3

Case Studies

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