Human GFR alpha-1 Protein (Asp 25-Ser 424) [Fc] (VAng-1678Lsx)
Human GFR alpha-1 (GFRA1), Fc tag, is expressed in human 293 cells. (Uniprot ID: NP_665736.1)
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
GFRA1 (GDNF Family Receptor Alpha 1) is a a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. Diseases associated with GFRA1 include Hirschsprung Disease 1 and Multiple Endocrine Neoplasia, Type Iia.
Alternative Names
GFRA1, GDNFRA, RETL1, TRNR1, GDNFR, GFR-ALPHA-1, RET1L
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