Human HVEM Protein (Leu 39-Val 202) [Strep] (VAng-1730Lsx)

Human HVEM (TNFRSF14), Strep Tag, is expressed in human 293 cells. (Uniprot ID: NP_003811.2)

Datasheet

Specifications

Source

HEK293 Cells.

Target

HVEM

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

PBS, pH 7.4.

Purity

> 90% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

HVEM is a human cell surface receptor of the TNF-receptor superfamily. It is also known as CD270 in the cluster of differentiation classification. Moreover, it is also referred to as ATAR (another TRAF-associated receptor). This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.

Alternative Names

TNFRSF14, ATAR, HVEA, HVEM, LIGHTR, TR2, CD270