Recombinant HVEM Protein (Met1-Val202) [His] (VAng-Cr3834)

Recombinant HVEM Protein (Met1-Val202) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 36 kDa. (Uniprot ID: Q92956)

Datasheet

Specifications

Source

Mammalian cells

Target

HVEM

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

Protein lyophilized in sterile PBS/Protein store in sterile PBS.

Purity

> 90% pure by SDS-PAGE.

Storage

Store at -20 °C to -80 °C.

Antigen Information

Introduction

HVEM is a human cell surface receptor of the TNF-receptor superfamily. It is also known as CD270 in the cluster of differentiation classification. Moreover, it is also referred to as ATAR (another TRAF-associated receptor). This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.

Alternative Names

TNFRSF14; ATAR; CD270; HVEA; LIGHTR; TR2; tumor necrosis factor receptor superfamily member 14; TNF receptor superfamily member 14