Human OSM Protein (Ala 26-Arg 252) (VAng-2622Lsx)
Human Oncostatin M protein, was expressed in human 293 cells. (Uniprot ID: NP_065391.1)
Datasheet
Specifications
Source
HEK293 cells
Target
Oncostatin M
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
OSM (Oncostatin M) is a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Diseases associated with OSM include Kaposi Sarcoma and Indolent Myeloma.
Alternative Names
OSM, MGC20461, Oncostatin M
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