Human SMAC Protein (Ala 56-Asp 239) [His] (VAng-2750Lsx)
Human SMAC protein, His tag, was expressed in human 293 cells. (Uniprot ID: NP_063940)
Datasheet
Specifications
Source
HEK293 cells
Target
SMAC
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
20 mM HEPES, 150 mM NaCl, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
DIABLO (Diablo IAP-Binding Mitochondrial Protein) is an inhibitor of apoptosis protein (IAP)-binding protein. The mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64.
Alternative Names
DIABLO, SMAC
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