Rat IGF-I R Protein (Glu 31-His 936) (VAng-1952Lsx)
Rat IGF-I R (CD221) is expressed in human 293 cells. (Uniprot ID: P24062-1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
IGF1R
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
IGF1R (Insulin Like Growth Factor 1 Receptor) binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
Alternative Names
IGF1R, IGFR, JTK13, CD221, MGC142170, MGC142172, MGC18216
Related Product
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