CD33

CD33 is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. The extracellular portion of this receptor contains two immunoglobulin domains (one IgV and one IgC2 domain), placing CD33 within the immunoglobulin superfamily. The intracellular portion of CD33 contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that are implicated in inhibition of cellular activity.It is the target of gemtuzumab ozogamicin, an Antibody-drug conjugate for the treatment of patients with acute myeloid leukemia.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-Cr3756 Recombinant CD33 Protein (Met1-His259) [His] Mammalian cells Recombinant CD33 Protein (Met1-His259) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 40-46 kDa. (Uniprot ID: P20138) CD33 Tumor Antigens Datasheet 100 µg Inquiry
VAng-Cr3927 Recombinant Mouse CD33 Protein (aa 1-240) [Fc] Mouse Recombinant Mouse CD33 Protein (Met 1-Glu 240) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 51.6 kDa. (Accession ID: Q63994-1) CD33 Tumor Antigens Datasheet 100 µg Inquiry
VAng-Cr3928 Recombinant Human CD33 Protein (aa 1-259) [Fc] Human Recombinant Human CD33 Protein (Met1-His259) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 53.1 kDa. (Accession ID: AAH28152.1) CD33 Tumor Antigens Datasheet 100 µg Inquiry
VAng-2717Lsx Human CD33 Protein (Asp 18-His 259) [Llama IgG2b Fc Tag] HEK293 cells Human Siglec-3 (CD33) protein, Llama IgG2b Fc Tag, was expressed in human 293 cells. (Uniprot ID: AAH28152.1) CD33 Tumor Antigens Datasheet 100 µg Inquiry
VAng-2718Lsx Biotinylated Human CD33 Protein (Asp 18-His 259) [Avi] [His] HEK293 cells Biotinylated Human Siglec-3 (CD33) protein, His tag and Avi tag, was expressed in human 293 cells. (Uniprot ID: AAH28152.1) CD33 Tumor Antigens Datasheet 25 µg Inquiry
VAng-2719Lsx Human CD33 Protein (Asp 18-His 259) [human IgG1 Fc tag] HEK293 cells Human Siglec-3 (CD33) protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: AAH28152.1) CD33 Tumor Antigens Datasheet 100 µg Inquiry
VAng-2720Lsx Human CD33 Protein (Asp 18-His 259) [His] HEK293 cells Human Siglec-3 (CD33) protein, His tag, was expressed in human 293 cells. (Uniprot ID: AAH28152.1) CD33 Tumor Antigens Datasheet 100 µg Inquiry

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