Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsThe HuFabL-4 Human Fab Antibody Library is an advanced tool designed for effective and high-quality antibody screening. Utilizing cutting-edge phagemid phage display technology, this library offers a diverse array of human Fab antibody fragments derived from non-immunized naïve donors. Ideal for a variety of antibody discovery projects, the HuFabL-4 library enables researchers to efficiently identify high-quality antibody candidates, offering an accessible and scalable approach to target identification.
| Species | Human | Library ID | HuFabL-4 |
| Display Technology | pIII-fusion, Phagemid phage display system | Library Format | Fab format |
| Vector System | Psd | Tags | 6×His and HA |
| Library Capacity | 1.9×1010 | Library Source | Human antibody genes from 100+ naïve donors |
| Host Strain |
TG1 cells for proliferation HB2151 cells for antibody production |
Helper Phage | M13KO7 |
The HuFabL-4 library demonstrates excellent performance in antibody screening through its consistently high success rates with protein targets and complex cell-based along with non-traditional targets. Our team could obtain functional high-affinity antibodies that maintain effectiveness against difficult targets and accelerate research progress with dependable results.
Tailored to meet your unique research needs, the HuFabL-4 library supports a wide variety of screening applications, including cell-based targets, peptides, small molecules, toxins, and more. Whether you're working with complex disease targets or novel biomolecules, we provide flexible solutions to ensure the success of your project.
More than 100 diverse human antibody donors provide the source material for the HuFabL-4 library which contains a comprehensive genetic pool of naïve human antibody genes. The extensive diversity enables better identification of optimal antibodies for your target which improves the probability of finding high-quality functional antibodies.
With a large capacity, the HuFabL-4 library supports both small- and large-scale screening without sacrificing the quality or accuracy of your results, allowing you to scale your project as needed with confidence.
Available Screening Service Types
Our HuFabL-4 library supports a wide array of screening services for different types of targets. We specialize in the following applications, providing you with the precise antibody solutions you need:
| Antibody Types: | |||
| Bispecific Antibodies | Anti-Idiotype Antibodies | Anti-Epitope Antibodies | Cell-Internalizing Antibodies |
| Target Types: | |||
| Membrane Protein Targets | Cell-based Targets | Enzyme Inhibitors | MHC-Peptide Complexes |
| Disease and Biomarker Targets: | Viral Antigens | Cancer Antigens | Receptor Targets |
| Small Molecule Targets | Toxin Targets | ||
Our Screening Process - Simple and Efficient
We need details about your target and any special needs you may have for your project objectives.
Using our HuFabL-4 library, we perform antibody screening via the phage display system, ensuring rapid identification of high-affinity antibodies specific to your target.
After screening, we provide a detailed report that includes the best candidate antibody sequences along with data on their binding affinity and specificity.
Our team stands ready to provide assistance with any questions or analysis needs during the project to ensure your experience remains smooth and successful.
Please note that we offer screening-only services and do not provide enriched libraries after multiple rounds of screening. Our focus is on delivering high-quality screening results for your specific target needs.
| Case: Antibody Screening for Protein with Fc Tag | |
| Starting Materials | Target protein T1, Fc tag |
| Solid-Phase Screening Strategy |
Pre-counter selection using Fc control Positive selection for target protein T1 |
| Key Results |
 Fig 1. Process monitoring of library screening stage.  Fig 2. Monoclonal phage ELISA of the randomly picked clones.  Fig 3. Summary of DNA sequencing results.  Fig 4. QC soluble ELISA of the unique binders. |
| Species | Antibody Library ID | Display Technology | Library Format | Library Size | Out-licensing |
| Human | HuScL-6 | pIII-fusion, Phagemid Phage Display | Naïve scFv | 2.1×1011 | Screening-only |
| HuScL-7 | pIII-fusion, Phagemid Phage Display | Naïve scFv | 1.1×1010 | ✔️ | |
| HuScL-3S | pIII-fusion, Phagemid Phage Display | Semi-synthetic scFv | >1.0×1011 | Screening-only | |
| HuFabL-4 | pIII-fusion, Phagemid Phage Display | Naïve Fab | 1.9×1010 | Screening-only | |
| HuFabL-5 | pIII-fusion, Phagemid Phage Display | Naïve Fab | 1.1×1010 | ✔️ | |
| HuFabssL-1 | pIII-fusion, Phagemid Phage Display | Naïve & synthetic Fab | 1.8×1010 | Screening-only | |
| HuscL-YDP-3 | Yeast Display | Naïve scFv | 1.9×108 | ✔️ |
Ready to Get Started?
today to discuss your project and receive a tailored quote. We’re here to support your research and help you find the ideal antibody solution for your work.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
