Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsPhage Display HuScL-3S Library represents a state-of-the-art resource designed for researchers seeking highly diverse and high-affinity antibody candidates. Leveraging advanced phage display technology, this library provides access to an enormous pool of human-derived antibodies, ensuring reliable results even for the most complex and diverse targets. Available for screening-only services, the HuScL-3S library enables researchers to achieve optimized, high-throughput antibody discovery for all their research objectives.
| Species | Human | Library ID | HuScL-3S |
| Display Technology | pIII-fusion, Phagemid phage display system | Library Format | VH-VL format scFv antibody library |
| Vector System | pCANTAB 5E | Tags | E tag |
| Library Capacity | >1.0×1011 | Library Source | Collections of human V genes from non-immunized donors introduced a synthetic trimer-codon HCDR3 |
| Host Strain |
TG1 cells for proliferation HB2151 cells for antibody production |
Helper Phage | M13KO7 |
The HuScL-3S library offers high efficiency and diversity, resulting in antibody candidates with exceptional target specificity and affinity. Our library presents a wide range of human-derived antibodies to boost your research results when you screen for membrane proteins, small molecules, or disease biomarkers.
The HuScL-3S library delivers unmatched versatility through its ability to target a wide range of antigens. We customize our screening process to match your project's distinct needs while delivering precise results for difficult and intricate targets.
Built from semi-synthetic human antibody genes and utilizing trimer-codon randomization in the HCDR3 region, the HuScL-3S library features a diverse and high-variability pool of antibody candidates. This enhanced diversity increases your chances of discovering antibodies with optimal affinity, specificity, and functional efficacy for your specific research needs.
With a capacity exceeding 1.0×1011, the HuScL-3S library is fully scalable, making it ideal for both small-scale and large-scale screening projects. Whether you are screening a few targets or conducting a comprehensive investigation across multiple targets, our high-throughput screening system ensures seamless execution and reliable, high-quality results every time.
Available Screening Service Types
We offer a comprehensive range of screening services designed to meet the diverse needs of your research projects. Some of the target types and antibody formats we have successfully worked with include:
| Antibody Types: | |||
| Bispecific Antibodies | Anti-Epitope Antibodies | Cell-Internalizing Antibodies | |
| Target Types: | |||
| Membrane Protein Targets | Cell-based Targets | Enzyme Inhibitors | MHC-Peptide Complexes |
| Disease and Biomarker Targets: | Viral Antigens | Cancer Antigens | Receptor Targets |
| Small Molecule Targets | Toxin Targets | ||
How Our Screening Process Works
Provide detailed information about your target, such as the protein, peptide, or cell-based target, including any relevant structural or sequence data.
Multiple rounds of panning are performed to identify high-affinity, specific antibodies that bind exclusively to your target, using our advanced screening protocols.
Receive a comprehensive report containing:
Top antibody candidate sequences.
Binding affinity and specificity data.
Our expert team offers ongoing support for antibody validation, functional assays, and guidance on next steps to ensure the antibodies perform optimally in your application.
Important Notes:
| Case: Screening for Protein Target | |
| Starting Materials |
Biotinylated cancer antigen protein T1 Control protein non-target cancer antigen protein C1 |
| In-Solution Screening Strategy |
Pre-counter selection using control protein C1. Positive selection for biotinylated protein T1. |
| Key Results |
|
| Species | Antibody Library ID | Display Technology | Library Format | Library Size | Out-licensing |
| Human | HuScL-6 | pIII-fusion, Phagemid Phage Display | Naïve scFv | 2.1×1011 | Screening-only |
| HuScL-7 | pIII-fusion, Phagemid Phage Display | Naïve scFv | 1.1×1010 | ✔️ | |
| HuScL-3S | pIII-fusion, Phagemid Phage Display | Semi-synthetic scFv | >1.0×1011 | Screening-only | |
| HuFabL-4 | pIII-fusion, Phagemid Phage Display | Naïve Fab | 1.9×1010 | Screening-only | |
| HuFabL-5 | pIII-fusion, Phagemid Phage Display | Naïve Fab | 1.1×1010 | ✔️ | |
| HuFabssL-1 | pIII-fusion, Phagemid Phage Display | Naïve & synthetic Fab | 1.8×1010 | Screening-only | |
| HuscL-YDP-3 | Yeast Display | Naïve scFv | 1.9×108 | ✔️ |
Get Started Today!
Whether you're developing diagnostic reagents, therapeutic candidates, or novel research tools, Creative Biolabs' HuScL-3S screening service is the solution to accelerate your antibody discovery. Have questions? We're here to tailor our services to your needs.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
