pBOOST2 Human cIRF7/3 (VCar-Ly035)
Express a human super-activated IRF7/3 chimeric gene.
Source
Human super-activated chimeric IRF-7/IRF-3 gene
Type
Dendrimers&Cyclopeptides
Applications
For DNA vaccine delivery.
Introduction
pBOOST2 cIRF7/3 plasmids express a human or murine super-activated IRF7/3 chimeric gene. IRF7/3 increase both Th1 T-cell and Th2 antibody responses by transactivating different target promoters. To exploit the biological features of both IRFs, a chimeric form of IRF-7 and IRF-3 was generated by combining the DNA binding specificity of IRF-7 with the strong transactivation capacity of super-activated IRF-3. cIRF7/3 plasmid expresses the transgene under the control of the strong and ubiquitous EF-1α/HTLV composite promoter.
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.