pBOOST2 Murine mIRF-3 (VCar-Ly034)
| CAT | Size | Price | Quantity | |
|---|---|---|---|---|
| VCar-Ly034 |
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Express a murine mutant interferon regulatory factor 3 (IRF-3) gene.
Datasheet
Specifications
Source
Murine super-activated IRF-3 gene
Target
DVA vaccine
Type
Dendrimers&Cyclopeptides
Applications
For DNA vaccine delivery.
Quantity
20 µg
Antigen Information
Introduction
pBOOST2 mIRF-3 plasmid expresses a human or murine mutant interferon regulatory factor 3 (IRF-3) gene which has been shown to primarily increase Th1 T-cell responses. In addition, it express the transgene under the control of the strong and ubiquitous EF-1α/HTLV composite promoter. A constitutively active form of IRF-3 was generated by creating a single point mutation of Ser396 to Asp. This super-activated IRF-3 presents a up to 10-fold enhanced transactivating potential over the wild-type IRF-3 for the IFN-α and IFN-β promoters.
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
