Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsScientists at Creative Biolabs have rich experience in the development of anti-small molecules hybridoma. We are so confident about our expertise and success rate that we guarantee our services with guaranteed positive clones. At Creative Biolabs, we are dedicated to helping you secure the potential of your project by providing you with a comprehensive project plan for hybridoma development. With passion and know-how, Creative Biolabs has developed a series of small molecules and heavy metal compound antibodies. We hope that our technical services and products can bring you convenience! Looking forward to creating your individually tailored hybridoma development plan!
Small molecule antibodies are widely used in various fields such as in environmental monitoring and food safety. Small molecules include diverse compounds such as antibiotics, pesticides, toxins, drugs, chemicals, lipids, vitamins, amino acids. Generally, these small molecules could be detected by physico-chemical technology such as chromatography or coupled chromatography-mass spectroscopy. However, the use of these methods requires expensive material and highly skilled staff with biology as well as chemistry backgrounds. On the contrary, anti-small molecules antibodies allow the detection, visualization, and even quantification of small molecules at low cost and high sensitivity.
On the other hand, anti-small molecules antibodies are rapidly gaining widespread attention in the therapeutic field and their applications could represent an alternative solution to the use of antibody-drug conjugates (ADC). Ani-small molecules antibody could be used to deliver the payload to the right target.
Small molecules do not represent good immunogens mainly due to their small size. Generating antibodies against small molecules necessitates small molecules to become immunogenic. To solve this problem, small molecules could be conjugated to a carrier molecule such as KLH, BSA, OVA, CGG. However, there can be challenges in conjugating the small molecule to a carrier protein and then generating the desired immune response specific to the small molecule and not the carrier protein or linker.
Creative Biolabs recommends analyzing the immunogenic variables of the small molecule including the chemical structure, conjugation method, cross-linking between the small molecule and protein carrier, the orientation of the hapten on the carrier protein, and linkers used. Besides, the antigen presentation should mimic the same orientation as the assay. We can design an immunization strategy to increase the immune response against the small molecule through adjuvants used, immunization methods, and immunization schedules.
Fig.1 Main factors for small molecule-carrier development.
Creative Biolabs provides custom anti-small molecule mAb development services through hybridoma technology. Moreover, competitive ELISA-validated hapten-carrier conjugate and antibody are available for you.
At the end of each phase, for transparent projects with limited risk and deferred costs.
Our combined chemistry and biology expertise guarantees the design and synthesis of the best small molecule-carrier conjugate. As a pioneer in antibody generation, Creative Biolabs can generate anti-small molecules hybridoma and further Bulk Antibody Production for worldwide clients. Please contact us for more information.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
