shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(MORC2-shRNA-Seq1)(CAT#: AdV-SI0375WQ)

This product is a MORC2-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The MORC2 gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The expression of MORC2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype HAdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Insert MORC2-shRNA-Seq1
Related Target/Protein MORC2
Region CDS
TargetSeq CATCTATAAGTACTCTCCATT
NCBI RefSeq NM_014941
Alternative Names ZCW3; CMT2Z; ZCWCC1
Titer >1*10^10 GC/mL
Related Diseases Breast cancer
Target Gene
Gene ID 22880
Uniprot ID Q9Y6X9

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