shRNA Lentivirus (self-inactivating), p7SK-(SERINC5-shRNA-Seq1)(CAT#: LV-SI1498WQ)

This product is a SERINC5-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The SERINC5 gene impairs the penetration of the viral particle into the cytoplasm and enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes. The expression of SERINC5-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.