shRNA Lentivirus (self-inactivating), pU6-(Armc5-shRNA-Seq1)(CAT#: LV-SI2334WQ)

This product is a Armc5-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The Armc5 gene encodes a member of the ARM (armadillo/beta-catenin-like repeat) superfamily. Mutations in this gene are associated with primary bilateral macronodular adrenal hyperplasia, which is also known as ACTH-independent macronodular adrenal hyperplasia 2. The expression of Armc5-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.