siRNA, Anti-PGLS, 2'-F/2'-OMe/Ribo/Backbone-modified(CAT#: SIRGT71622WQ-2OMe)

The product SIRGT71622WQ-2OMe is a type of small interfering RNA (siRNA) that targets PGLS gene and regulates the expression of gene. The siRNA interferes with the expression of PGLS gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_012088.2
Alternative Names 6PGL; HEL-S-304
Related Diseases Persistent Generalized Lymphadenopathy
Purification HPLC
Target Gene
Gene ID 25796
Uniprot ID O95336
Sub Cat Target Species Modification Scale  
SIRGT72622WQ-2F PGLS Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT71622WQ-RB PGLS Human Ribo-modified Inquiry
SIRGT72622WQ-BB PGLS Human Backbone-modified Inquiry

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