siRNA, Anti-TIRAP, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT62314WQ-2F)

The product SIRGT62314WQ-2F is a type of small interfering RNA (siRNA) that targets TIRAP gene and regulates the expression of gene. The siRNA interferes with the expression of TIRAP gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001039661.1
Alternative Names BACTS1; Mal; MyD88-2; wyatt
Related Diseases Bacteremia 1
Purification HPLC
Target Gene
Gene ID 114609
Uniprot ID P58753
Sub Cat Target Species Modification Scale  
SIRGT81211WQ-2OMe Tirap Mouse 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT82211WQ-2F Tirap Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT84211WQ-LNA Tirap Mouse Locked Nucleic Acid (LNA) Inquiry
SIRGT61314WQ-RB TIRAP Human Ribo-modified Inquiry
SIRGT81211WQ-RB Tirap Mouse Ribo-modified Inquiry
SIRGT82211WQ-BB Tirap Mouse Backbone-modified Inquiry

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