siRNA, Anti-FBL, 2'-F/2'-OMe/2'-MOE/LNA-modified(CAT#: SIRGT06405WQ-2OMe)

The product SIRGT06405WQ-2OMe is a type of small interfering RNA (siRNA) that targets FBL gene and regulates the expression of gene. The siRNA interferes with the expression of FBL gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001436.3
Alternative Names FIB; FLRN; Nop1; RNU3IP1
Related Diseases Diffuse Scleroderma, Systemic Scleroderma
Purification HPLC
Target Gene
Gene ID 2091
Uniprot ID P22087
Sub Cat Target Species Modification Scale  
SIRGT07405WQ-2F FBL Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08405WQ-2MOE FBL Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09405WQ-LNA FBL Human Locked Nucleic Acid (LNA) Inquiry

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