siRNA, Anti-JAG2, 2'-F/2'-OMe/LNA/Ribo-modified(CAT#: SIRGT11404WQ-2OMe)
The product SIRGT11404WQ-2OMe is a type of small interfering RNA (siRNA) that targets JAG2 gene and regulates the expression of gene. The siRNA interferes with the expression of JAG2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_002226.4; NM_145159.2 |
| Alternative Names | HJ2; SER2 |
| Related Diseases | Ossifying Fibroma, Alagille Syndrome 1 |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT12404WQ-2F | JAG2 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT14404WQ-LNA | JAG2 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT11404WQ-RB | JAG2 | Human | Ribo-modified |