siRNA, Anti-JAG2, 2'-F/2'-OMe/LNA/Ribo-modified(CAT#: SIRGT11404WQ-2OMe)

The product SIRGT11404WQ-2OMe is a type of small interfering RNA (siRNA) that targets JAG2 gene and regulates the expression of gene. The siRNA interferes with the expression of JAG2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002226.4; NM_145159.2
Alternative Names HJ2; SER2
Related Diseases Ossifying Fibroma, Alagille Syndrome 1
Purification HPLC
Target Gene
Gene ID 3714
Uniprot ID Q9Y219
Sub Cat Target Species Modification Scale  
SIRGT12404WQ-2F JAG2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT14404WQ-LNA JAG2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11404WQ-RB JAG2 Human Ribo-modified Inquiry

Related Products