siRNA, Anti-MUC5AC, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11882WQ-2OMe)

The product SIRGT11882WQ-2OMe is a type of small interfering RNA (siRNA) that targets MUC5AC gene and regulates the expression of gene. The siRNA interferes with the expression of MUC5AC gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001304359.1
Alternative Names MUC5; TBM; leB; mucin
Related Diseases Barrett Esophagus, Biliary Papillomatosis
Purification HPLC
Target Gene
Gene ID 4586
Uniprot ID P98088
Sub Cat Target Species Modification Scale  
SIRGT12882WQ-2F MUC5AC Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13882WQ-2MOE MUC5AC Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14882WQ-LNA MUC5AC Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11882WQ-RB MUC5AC Human Ribo-modified Inquiry
SIRGT12882WQ-BB MUC5AC Human Backbone-modified Inquiry

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