siRNA, Anti-SPP2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21378WQ-2OMe)

The product SIRGT21378WQ-2OMe is a type of small interfering RNA (siRNA) that targets SPP2 gene and regulates the expression of gene. The siRNA interferes with the expression of SPP2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_006944.2
Alternative Names SPP-24; SPP24
Related Diseases Retinitis Pigmentosa
Purification HPLC
Target Gene
Gene ID 6694
Uniprot ID Q13103
Sub Cat Target Species Modification Scale  
SIRGT22378WQ-2F SPP2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23378WQ-2MOE SPP2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24378WQ-LNA SPP2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21378WQ-RB SPP2 Human Ribo-modified Inquiry
SIRGT22378WQ-BB SPP2 Human Backbone-modified Inquiry

Related Products