Transfection Technologies

Tumor immunotherapy has become a hot topic in the field of cancer prevention. Relying on rich professional knowledge and the most advanced technology platform, Creative Biolabs supports the discovery of cell and gene therapy through a strategy-based and consultative approach. Comprehensive technical services can be offered to you, including TCR design construction and plasmid GLP production, CAR design construction and plasmid GLP production, programming CAR technologies and oncolytic virus construction.

Transfection Technologies Service

We are committed to providing an efficient and reasonable transfection technology platform to you.

Summary of Production of the GMP Challenge Stock.Fig.1 Patient-centered gene-engineered T-cell therapy of cancer.

Aided by the advanced expertise and technologies, our scientists genetically modified T cells for the CAR and flexibly used a variety of methods to convert CAR construction into T cells. During the whole process, the transfection plays an important role in T-cell therapy (Fig.1).

Virus transfection

With outstanding professional technology and rich experience, creative Biolabs are capable of offering you virus transfection services at the highest level, including retroviral transfection and lentiviral transfection.

CAR-T Cell Viral Transfection Approaches (Creative Biolabs). Fig.2 CAR-T Cell Viral Transfection Approaches (Creative Biolabs)

Electroporation

Compared with virus transfection and transposon transfection, electroporation is easier to operate, in addition, it can save time and energy for large-scale cell research.

Transposons transfection

The optimized transposon transfection service has a higher ability to carry the target DNA. Through our standard GLP experimental platform, sleeping beauty (SB) and piggyBac (PB) systems can be provided easily.

Highlights

Tailor the most favorable approach for your project according to your specific requirements and our characteristic platform technology.

Creative Biolabs has the management standard backstage knowledge platform, can design the experiment plan according to your project request.

Please contact us now and we will get back to you as soon as possible.

Reference

  1. Johnson L A; June C H. Driving gene-engineered T cell immunotherapy of cancer[J]. Cell Research. 2017, 27(1): 38-58.

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