Bioassay Services

Creative Biolabs offers biomarker identification, assay development, and validation services. We provide the quality, sensitivity, and accuracy needed to make critical go or no-go decisions in drug discovery and development, helping move your research forward.

ADCC, CDC, and ADCP are critical immune mechanisms for antibody-based therapies. Creative Biolabs provides advanced ADCC/CDC/ADCP levels detection services to help optimize antibody designs and enhance these effector functions, ensuring the efficacy and potency of your therapeutic antibodies.

Immunoassays are fast and accurate tests that use an antibody's specific binding ability to detect a target compound. Based on a unique immune response, these tests track various proteins and antibodies, providing a reliable method for detecting specific molecules in biological systems.

Immune checkpoints, consisting of co-inhibitory and co-stimulatory pathways on effector cells, are crucial for immune regulation. Creative Biolabs, with years of experience, has developed a novel set of cell-based assays. These assays use cutting-edge technology and advanced knowledge to quantitatively and effectively assess the mechanism of action of immunotherapeutic antibodies.

Understanding the binding interactions between therapeutic candidates and their biological targets is essential for optimizing efficacy, safety, and pharmacokinetics. Creative Biolabs provides high-quality binding assay services for therapeutic antibody and protein development. Our services, which include FcR, FcRn, and C1q binding assays, use state-of-the-art technologies to deliver accurate, reliable, and reproducible results.

Tissue cross-reactivity (TCR) studies are crucial for pre-clinical development of therapeutic antibodies. Creative Biolabs' TCR services provide a powerful immunohistochemical assessment to identify potential cross-reactivity with a range of human tissues. This helps to identify non-target specific binding, providing important information about the immunological properties of the antibody and mitigating potential safety risks before Phase I clinical trials.

Understanding the functional capacity of immune cells is pivotal for advancing therapeutic strategies. Creative Biolabs introduces our immune cells function assay, a comprehensive service designed to elucidate the capabilities of various immune cell subsets, providing critical insights into immune responses and aiding in the development of next-generation immunotherapies.

Immuno-oncology is revolutionizing cancer therapy by training the immune system to selectively attack tumor cells. Creative Biolabs offers a broad portfolio of immuno-oncology assays to advance the development of promising cancer immunotherapies, including CAR-T therapies, checkpoint inhibitors, and oncolytic viruses.

Tumor markers are proteins or substances released by cancer cells or other cells during cancer or benign conditions. Creative Biolabs provides tumor marker assays that can provide information about a cancer's virulence and open the door to new treatment methods. With their in-house scientists and innovative platforms, they can help make your project a reality.

Epitopes, which are immunogenic antigen peptides, are recognized by immune cells. A thorough understanding of their molecular characteristics is essential for developing cancer immunotherapies. Creative Biolabs, with its extensive knowledge and experience in immune responses, offers various B-cell and T-cell-based assays for cancer epitope analysis.

Host cell proteins (HCPs) are process-related impurities that can compromise the efficacy and safety of biopharmaceuticals. As exogenous proteins, they can trigger an immune response in patients. Creative Biolabs offers a range of HCP analysis services and kits to ensure the quality and safety of your biologics by detecting and quantifying these impurities.

Cell surface markers, such as CD molecules, are crucial for evaluating immune cell function and distinguishing different cell types. Creative Biolabs provides services to identify these markers, helping to accelerate immunology research and understand immune cell dynamics.

Cell-based assays are valuable tools in drug discovery. Creative Biolabs has developed a panel of live cell assays to investigate basic cell biology and drug discovery, helping to reduce toxicity and accelerate the development of new drugs.

Cell adhesion is crucial in many biological processes, from immune responses to cancer progression. Creative Biolabs offers a comprehensive cell adhesion assay service to support researchers in studying these interactions, providing valuable insights into disease mechanisms and advancing the development of targeted therapies.

Cell migration is critical in biological processes like wound healing and cancer metastasis. Creative Biolabs' specialized cell migration assay services provide precise, high-throughput solutions for studying cellular motility. Our epidermal growth factor (EGF)-induced HaCaT Cell migration assay is particularly tailored for research on keratinocyte behavior and wound healing.

Cell cycle progression is crucial for understanding cell growth and the effects of therapeutic interventions. Creative Biolabs introduces our cell cycle progression assessment service, which provides a detailed analysis of cell cycle dynamics. This service uses advanced flow cytometry techniques to deliver a precise, cell-by-cell evaluation of cell cycle phases, helping researchers gain deeper insights into their studies.