Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsCreative Biolabs is proud to present our Phage Display Protease-10A HiAffi Tagged 10-mer Peptide Library, a versatile solution for screening high-specificity peptide substrates tailored to a specific protease. This library is meticulously designed to support your research in enzyme-substrate dynamics, biomarker discovery, and drug discovery. Allow Creative Biolabs to facilitate your next protease-targeted research endeavor.
| Library ID | Protease-10A | Library Format | HiAffi tagged 10 mer peptide library |
| Display Technology | M13 pIII fusion, phagemid phage display | Randomization | Trimer codon, avoid stop and non-sense codon |
| Vector System | pCDisplay-3D | Tags | Domain C of protein A |
| Library Capacity | 1.1×1010 | Host Strain | E. coli TG1 |
The Protease-10A library has been subjected to thorough quality control procedures, ensuring each peptide meets and exceeds the highest standards of performance and functionality. As a result of this unwavering commitment to quality, users are provided with a premium resource that can be trusted to offer unparalleled reliability and consistency in every aspect of their screening endeavors.
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Library Design Trimer Codon strategy, encoding 19 amino acids across 10 sites. |
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Library Capacity 1.1×1010
Library 1 Capacity (A, B, C): 3.6×109
Library 2 Capacity (D, E, F): 3.9×109 Library 2 Capacity (G, H, I): 3.5×109 |
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Pilot Sequencing Success Rate
90% (45/50 clones)
Library Accuracy
High Diversity
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Amino Acid Distribution  The observed frequencies of each amino acid were in agreement with the expected frequencies. The frequencies of amino acids ranged from 2.95 to 9.55%, except for C. |
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Our Protease-10A Peptide Library is specifically engineered to provide comprehensive and diverse peptide coverage, ensuring an exhaustive search of the peptide space for your target screening requirements. The library boasts a high-density design that maximizes the probability of identifying novel and high-affinity peptide binders for a wide array of biological targets.
Leveraging the power of phage display, we have created a robust platform for peptide screening, capable of isolating specific and high-affinity peptide ligands. This technology is compatible with a broad spectrum of target molecules, allowing for the discovery of therapeutic peptides with unparalleled sensitivity and specificity. It's an ideal choice for both fundamental research and translational studies.
With an expansive repertoire of peptide sequences and a capacity exceeding 10^9 unique peptide variants, our library provides a wealth of diversity. This rich resource is well-suited to a variety of applications, from biomarker discovery and drug development to the optimization of diagnostic assays.
The Protease-10A library is designed to be versatile and can be adapted to meet the demands of different screening environments. This flexibility ensures that peptide targets can be optimized to align with your specific research goals, whether it's enzyme inhibition, receptor interaction, or pathogen detection.
Our library is fully integrated with a cutting-edge high-throughput screening platform, facilitating rapid and large-scale screening processes. This integration significantly shortens the timeline for identifying potential drug candidates, streamlining your drug discovery process and bringing your solutions to market more quickly.
Tailored to identify peptide candidates that exhibit high specificity and affinity to your chosen targets, the TriCo-16 library is instrumental in reducing off-target effects. This focus on precision helps to enhance the therapeutic efficacy of your compounds and optimize your research outcomes.
| Research License (Academic) | Research License (Industry) | Commercial License |
| Epitope Specific Peptide Discovery | Cell-Targeted Peptide Discovery | Disease-Specific Peptide Discovery |
| Particulate Matter Binding Peptide Screening | Soft Matter Binding Peptide Screening |
To simplify the screening process, we offer a comprehensive, seamless workflow designed to save you time and effort while delivering high-quality antibody candidates tailored for your research or therapeutic needs.
| 1. Submit Your Target | 2. Phage Display Screening | 3. Result Delivery | 4. Post-Screening Support |
| Optimized Substrate Selection for a Target Protease Using a Protease-10A Library | |||||
| Objective | The customer provided one protease, referred to as Target protease. We were contracted to identify the substrate peptide for the target from our custom-made Protease-10A Peptide Library. | ||||
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Creative Biolabs has a full range of premade peptide libraries to make peptide discovery fast and efficient. Our premade ready-to-use libraries are available as both cyclic and linear peptides and in a variety of lengths (9-mer, 16-mer, 20-mer), allowing for fast discovery of binding peptides to nearly any target, cell-penetrating/internalizing peptides, or other functional peptides. We also provide full service for completely custom peptide library design and synthesis - from design to delivery - based on your target of interest, format and screening strategy.
| Library ID | Display Technology | Library Format | Library Size | Out-licensing |
| TriCo-16 | pIII-fusion, True Phage Display | 16-mer peptide library | 1.1×1010 | ✔️ |
| TriCo-20 | pIII-fusion, True Phage Display | 20-mer peptide library | 1.3×1010 | ✔️ |
| TriCo-C9 | pIII-fusion, Phagemid Phage Display | Cyclic 9-mer peptide library | 1.1×1010 | ✔️ |
| TriCo-C9L | pIII-fusion, Phagemid Phage Display | Cyclic 9-mer peptide library | 6.8×1010 | Screening-only |
| Protease-10A | pIII-fusion, Phagemid Phage Display | HiAffi tagged 10 mer peptide library | 1.1×1010 | ✔️ |
Reach out today to learn more about our libraries and screening platforms, and how they can be applied to help you reach your research goals!
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
