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Phage Display TriCo-20 Linear 20-mer Peptide Library Licensing/Screening Service

Basic Information Features License Options Library Screening Cases Related Libraries Why Work with Us?

Can't find the peptide you need for drug development? Want to find and optimize peptides fast? Try the Phage Display TriCo-20 Linear 20-mer Peptide Library for peptide discovery! With long 20-mer peptides and advanced phage display platform, our TriCo-20 library is ready for fast and reliable peptide binder discovery to accelerate research for therapeutic and diagnostic applications. Accelerate your drug discovery, epitope mapping, and biomarker development with customizable screening for your specific target.

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Basic Library Information

Library ID TriCo-20 Library Format 20-mer peptide
Display Technology M13 pIII fusion, True phage display system Randomization Trimer codon, avoid stop and non-sense codon
Vector System M13KE Host Strain E. coli K12, ER2738
Library Capacity 1.3×1010 Tags /

Why Choose the TriCo-20 Library?

20-mer Peptides Provide Expanded Discovery Potential

Longer and extended peptides increase the possibility of identifying peptides that may be used for complex protein mimics or create new recognition patterns. In addition, the extended surface area allows a wider range of possible interactions than shorter peptide libraries.

Enhanced Diversity with Trimer Codon Randomization

TriCo (trimer codon) randomization ensures that each randomized position encodes a specific amino acid rather than a stop codon or uneven amino acid distribution. As a result, a functional and diversified peptide library is created, leading to a much better chance of finding a peptide with high-affinity binding.

High Library Capacity with Proven M13 Phage Display System

Utilizing the M13 pIII fusion system, this library employs a reliable and well-established true phage display technology. Peptides are displayed on the infectious phage particle, ensuring efficient selection, amplification, and minimal non-specific binding. The TriCo-20 Library offers a vast diversity of peptides, increasing the likelihood of finding highly specific and rare peptide binders for even the most challenging targets.

Customizable Screening Capabilities

The TriCo-16 library is adaptable to various screening conditions, allowing for the optimization of peptide targets specific to your research focus. Whether you are working on enzyme inhibition, receptor binding, or pathogen recognition, our library can be tailored to meet your exact requirements.

Flexible Application to Different Research Areas

Use the TriCo-20 library for a wide range of applications, including therapeutic peptide development, biomarker discovery, and diagnostic development. You can also use it for a wide range of biological targets.

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License Options for Research and Commercial Use

Research License (Academic)
  • For academic customers conducting research with publication purposes.
  • Customers are not permitted to amplify the library.
  • A copy of the antibody library is provided as a vial containing enough material for ten biopanning projects.
Research License (Industry)
  • For industry customers acquiring the library for research purposes.
  • Customers are permitted to amplify the library themselves, with no limitation on the amount of library.
  • Includes a vial of the library.
  • If customers prefer not to amplify the library themselves, a continuous supply of material is available through additional purchase.
Commercial License
  • Customers are not permitted to sell the library as a product or service to other customers, and are not allowed to distribute the library to any third party in any form.

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High-Efficiency Screening for Precision Research

From rare epitopes to complex materials, our comprehensive peptide library screening efficiently identifies top-performing binders with unmatched speed, accuracy, and reproducibility - accelerating your journey from concept to candidate. By combining extensive library diversity with rigorous selection protocols and data-driven analysis, we quickly deliver peptide leads tailored to your specific biological, device, or material needs.

Customizable Screening for Any Research Focus

End-to-End Screening Workflow

Creative Biolabs' simple, all-inclusive, no-fuss workflow is designed to take the work out of screening, save you time and effort, and deliver high-quality peptide candidates ready for your research or therapeutic development.

1. Submit Your Target 2. Phage Display Screening 3. Result Delivery 4. Post-Screening Support

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Screening in Action: Case Studies and Results

Soft Matter Binding Peptide Screening Using TriCo-20 Library
In this project, we demonstrate our cutting-edge approach to peptide screening, tailored specifically for Soft Matter materials. Using a premade peptide library combined with a customized biopanning strategy, we achieved remarkable results that go beyond traditional screening methods. Our process is designed to deliver highly specific and affinity-targeted peptides, addressing the unique challenges our clients face.
Advanced Screening Process
Fig 1. Graph illustrating the screening outcomes. (Creative Biolabs Original).
  • We utilized a four-round biopanning strategy ensuring comprehensive coverage and robust enrichment.
  • The data clearly showed significant enrichment for the target peptides, with minimal variation between different screening groups, reflecting our method's precision in identifying the best candidates.
Binder Validation for Precision and Quality
Fig 2. Graph displaying the validation results. (Creative Biolabs Original). Fig 3. Graph displaying the NGS analysis results. (Creative Biolabs Original).
  • To confirm the efficacy of the enriched library, we randomly selected 92 clones and subjected them to monoclonal phage ELISA.
  • Half of the clones tested positive for binding activity, and we proceeded with sequencing these promising candidates for preliminary identification.
  • Furthermore, we implemented NGS deep sequencing on the second-round enriched library, generating a vast dataset of peptide sequences.
  • From this, we identified the top peptide candidates, which were delivered to the client for internal validation and further development.
Client-Centered Results Positive Feedback
The client's feedback was overwhelmingly positive. Several of the top-ranked peptides exhibited the required affinity and specificity, making them ideal for the client's specific applications in Soft Matter material research. This success highlights our ability to meet the exact needs of our clients with tailored, high-quality peptide solutions.

Additional Premade Peptide Libraries Available

Creative Biolabs offers a comprehensive selection of premade sdAb libraries derived from camel, alpaca, and humanized sources. Available in both synthetic and natural formats, these libraries are designed to support a wide array of research applications, from target discovery to therapeutic development. Our expert screening services help identify high-affinity binders, ensuring reliable and accurate results. We also offer flexible licensing options, allowing you to integrate our libraries into your own research and product development with ease.

Library ID Display Technology Library Format Library Size Out-licensing
TriCo-16 pIII-fusion, True Phage Display 16-mer peptide library 1.1×1010 ✔️
TriCo-20 pIII-fusion, True Phage Display 20-mer peptide library 1.3×1010 ✔️
TriCo-C9 pIII-fusion, Phagemid Phage Display Cyclic 9-mer peptide library 1.1×1010 ✔️
TriCo-C9L pIII-fusion, Phagemid Phage Display Cyclic 9-mer peptide library 6.8×1010 Screening-only
Protease-10A pIII-fusion, Phagemid Phage Display HiAffi tagged 10 mer peptide library 1.1×1010 ✔️

Why Work with Us?

Blood-Brain Barrier (BBB) Specific SdAb
Highly Specific Peptides

Tailored to bind precisely to your material of interest.

Blood-Brain Barrier (BBB) Specific SdAb
Faster Results

Our advanced screening platform ensures quick, high-quality results, helping you move from discovery to application faster.

Blood-Brain Barrier (BBB) Specific SdAb
Expert Guidance

Our seasoned team offers continuous support, from initial screening to final antibody validation, ensuring a seamless research experience.

Blood-Brain Barrier (BBB) Specific SdAb
Custom Solutions

Services are tailored to your specific target, guaranteeing the selection of the most relevant antibodies for your unique project needs.

Blood-Brain Barrier (BBB) Specific SdAb
Proven Success

Delivering peptides with both affinity and specificity, directly aligned with client needs.

Blood-Brain Barrier (BBB) Specific SdAb
Reproducible and Scalable

With robust systems in place, we provide reproducible results across multiple rounds of screening, making us ideal for large-scale discovery projects.

Get in Touch for Your Custom Quote

Contact us for more information on how our libraries and screening platforms can help you achieve your research goals!


All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

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