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NativeExtract™ Recombinant Full Length Human TRPM1 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW190)

This product is recombinant Human TRPM1 protein in native nanodisc form. The synthetic compound we developed can solubilize the TRPM1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TRPM1
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 182.2 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • TRPM1
  • Full Name
  • Transient Receptor Potential Cation Channel Subfamily M Member 1
  • Introduction
  • This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants.
  • Alternative Names
  • Transient Receptor Potential Cation Channel Subfamily M Member 1; Long Transient Receptor Potential Channel 1; Melastatin-1; LTRPC1; MLSN1; Transient Receptor Potential Cation Channel, Subfamily M, Member 1

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