Are you struggling with slow antibody development, limited antibody diversity, or poor specificity in target recognition? Our AlVHHL-1 Alpaca Single Domain Antibody Library can help you rapidly generate high-affinity, highly specific antibodies through state-of-the-art phage display technology. By leveraging a naïve sdAb library derived from alpacas, we provide you with access to a diverse and powerful toolkit for accelerating your research and therapeutic developments.
| Species | Alpaca | Library ID | AlVHHL-1 |
| Display Technology | M13 pIII fusion, Phagemid phage display system | Library Format | Naïve VHH |
| Vector System | pMECS | Tags | HA, His tag |
| Library Capacity | 1.35×1010 | Library Source | Collections of antibody genes from 25 alpaca lymphocytes |
| Host Strain |
TG1 cells for proliferation HB2151 cells for antibody production |
Helper Phage | M13KO7 |
We maintain the highest quality standards for our library, ensuring consistent and reliable performance for your antibody discovery projects and offering you the best starting point for your experiments.
Library Capacity 1.2×1010![]() Library 1 (Figure ABC) Capacity 7.1×109 Library 2 (Figure DEF) Capacity 6.4×109 |
Insertion Rate 100% (colony PCR) Sequencing Success Rate 95% (38/40 clones) Library Accuracy 92.1% (35/38 clones) High Diversity 35 unique clones
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Unmatched Specificity & Affinity The AlVHHL-1 alpaca sdAb library excels in generating antibodies with exceptional specificity and high affinity. The smaller, more compact sdAbs offer superior target recognition, making them highly effective even in challenging environments, such as diagnostics or in vivo applications. |
Robust Stability & Compact Size sdAbs measure only 1/10 the size of standard antibodies which enables them to penetrate tissues more efficiently and attach to hidden or difficult-to-reach epitopes. The ability of these molecules to maintain stability across extreme pH levels and temperature changes makes them perfect for multiple uses including laboratory tests and medical treatments where typical antibodies prove ineffective. |
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Fast & Scalable Screening Optimized for rapid screening, this library accelerates the identification of high-affinity binders. Our advanced platform ensures that you receive precise, effective antibody candidates significantly faster than traditional methods, streamlining your antibody discovery process and reducing time to results. |
Comprehensive Target Range The AlVHHL-1 library delivers extensive antigen coverage through its collection of varied sdAbs from multiple alpacas. The library contains a wide range of binding candidates for proteins, peptides, and complex biomolecules to help you pick perfect antibodies for your specific requirements. |
Creative Biolabs' AlVHHL-1 Library is delivered with all the essential materials to ensure smooth and efficient integration into your research:
Our expert team will discuss your project’s needs to determine the best way to integrate the library into your research.
Based on your goals, we will provide a detailed plan on how to make the best use of the AlVHHL-1 Library in your antibody discovery process.
Once you confirm your order, we will promptly prepare and ship the library to your laboratory.
Upon receiving your order, you will get:
| Phagemid Library in E. coli TG1 | Phage Library | Host Strains |
| Helper Phage | Sequencing Primers | Library Manual (for smooth execution) |
Our dedicated team will provide continuous support throughout your project to ensure smooth execution and successful outcomes.
Creative Biolabs offers flexible and tailored licensing options to suit your specific needs. Limited Licensing allows users to access the AlVHHL-1 Library for non-commercial or early-stage research applications. This licensing option enables academic, exploratory and preclinical research projects to utilize the library under specific usage restrictions.
For those seeking alternatives to alpaca-derived sdAbs, our team offers camel and alpaca sdAb libraries, which deliver a broad variety of high-affinity binders similar to those found in alpaca sources. Specialized libraries created for diagnostic and therapeutic purposes feature antibodies that exhibit exceptional stability and precise target specificity. Our portfolio includes humanized sdAb libraries and the design of these libraries focuses on minimizing human immune reactions which makes them perfect for therapeutic purposes that require minimizing the immunogenicity. Our comprehensive sdAb libraries supply researchers and clinicians with essential resources for sophisticated investigation and drug development.
| Antibody Library ID | Display Technology | Library Format | Library Size | Out-licensing |
| AlVHHL-1 | pIII-fusion, Phagemid Phage Display | Naïve VHH | 1.35×1010 | ✔️ |
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AlVHHL-2 �� Highly Recommended |
pIII-fusion, Phagemid Phage Display | Naïve VHH | 1.5×1011 | Screening-only |
Contact our team today to begin your journey with the AlVHHL-1 library and take the next step toward cutting-edge antibody discovery!
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.