Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsThe LlaVHHL-2 Llama Naïve Single Domain Antibody Library is a state-of-the-art resource for efficient, high-quality antibody screening. Designed to meet the diverse needs of researchers, this library provides access to a rich pool of sdAbs derived from llama naïve antibody genes. With our high success rate in protein target screening and strong capabilities for screening cell-based and other complex targets, we are confident that our library can deliver exactly what you need to advance your research.
| Species | Llama | Library ID | LlaVHHL-2 |
| Species | Llama | Library ID | |
| Display Technology | M13 pIII fusion, Phagemid phage display system | Library Format | Naïve VHH |
| Vector System | pCantab 5E | Tags | E tag |
| Library Capacity | 1.8×1010 | Library Source | Collections of antibody genes from 30 none immunized llamas |
| Host Strain |
TG1 cells for proliferation HB2151 cells for antibody production |
Helper Phage | M13KO7 |
The LlaVHHL-2 Library delivers versatile screening methods that can effectively identify various target types such as proteins, peptides and small molecules. The ability to adjust screening protocols enables researchers to find the best antibody candidates that match their unique study requirements. The ability to customize screening protocols supports the efficient identification of high-affinity binders which enhances success rates across multiple applications.
The small size and high stability of llama-derived sdAbs make them perfect for binding complex antigens that are challenging to target. Llama-derived sdAbs benefit from their small size and high stability which together with remarkable binding affinity result in excellent tissue penetration and performance under extreme conditions. Llama sdAbs give researchers significant benefits when they explore tough research targets especially within diagnostic testing and targeted treatment development.
The LlaVHHL-2 Library originates from non-immunized Llamas which creates a genetically diverse pool of native sdAbs. The natural diversity within this system substantially boosts the probability of finding high-affinity binders that work across various molecular targets. The library maintains a natural abundance of sdAbs by sourcing from non-immunized donors which boosts the likelihood of identifying effective binders for challenging targets.
The high-throughput screening platform speeds up antibody discovery by reducing the time required to identify and validate promising candidates. Our tailored screening approaches guarantee that only top-performing binders move forward to additional development stages. The integrated streamlined methodology together with expert assistance and strong support enables fast advancement from discovery to candidate selection to speed up your research and clinical timelines while ensuring superior quality and precision.
Enhance your research capabilities through Creative Biolabs' phage display screening services which utilize the LlaVHHL-2 Library. Our system delivers high-quality, cost-effective results through its flexible, efficient, and scalable design. We guide you through the rapid and dependable discovery of optimal single-domain antibodies to guarantee project success from start to finish. Our system is built for flexibility, efficiency, and scalability, delivering high-quality, cost-effective results. We help you discover the perfect single-domain antibodies quickly and reliably, ensuring success at every stage of your project.
Our LlaVHHL-2 Library provides comprehensive antibody development services, tailored to your specific project needs:
| Antibody Types: | |||
| Bispecific Antibodies | Anti-Idiotype Antibodies | Anti-Epitope Antibodies | Cell-Internalizing Antibodies |
| Target Types: | |||
| Membrane Protein Targets | Cell-based Targets | Enzyme Inhibitors | MHC-Peptide Complexes |
| Disease and Biomarker Targets: | Viral Antigens | Cancer Antigens | Receptor Targets |
| Small Molecule Targets | Toxin Targets | ||
We understand that time is of the essence in research, which is why our platform is built for speed and reliability. You can count on rapid turnaround times without the burden of managing the complex screening process.
Provide us with the target details (protein, peptide, small molecules, etc.).
We conduct phage display screening with the LlaVHHL-2 Library to find high-affinity binders.
You will receive detailed results with candidate antibody sequences and binding affinities.
Our team provides continuous support throughout the screening process.
Note: We provide screening-only services, and do not offer enriched libraries after multiple rounds of screening. Our focus is on providing you with high-quality screening results for your specific targets.
| Case: Screening for Anti-Epitope Antibody | |
| Starting Materials |
Target biotinylated epitope peptide T1 Control biotinylated epitope peptide C1 Control biotinylated epitope peptide C2 |
| In-Solution Screening Strategy |
Pre-counter selection using control epitope peptide C1 + C2 Positive selection for biotinylated epitope peptide T1 |
| Key Results |
  After four rounds of screening, we identified high-affinity binders with strong specificity to the target epitope peptide T1. These were further validated using soluble ELISA, yielding promising results. |
Creative Biolabs offers premade sdAb libraries sourced from camels and alpacas along with humanized sdAbs. Some libraries offer customized screening services that aim at identifying specific binders while other libraries enable commercial research through licensing options. Our diverse antibody libraries encompass multiple species including mouse, rabbit and chicken to support different research needs and offer high-affinity specific binders. Clients can choose the best antibody library for their needs while taking advantage of multiple screening and licensing options to achieve successful project outcomes.
| Antibody Library ID | Display Technology | Library Format | Library Size | Out-licensing |
|
LlaVHHL-1 ⚡️ Hot Product |
pIII-fusion, Phagemid Phage Display | Naïve VHH | 1.9×1010 | ✔️ |
|
LlaVHHL-2 ⭐️ Premium Selection |
pIII-fusion, Phagemid Phage Display | Naïve VHH | 1.8×1010 | Screening-only |
|
LlaVHHL-S1 �� Highly Recommended |
pIII-fusion, Phagemid Phage Display | Synthetic VHH | 1.5×1011 | Screening-only |
|
LlaVHH-YPD-1 ⚡️ Hot Product |
Yeast Display | Naïve VHH | 1.5×108 | ✔️ |
for a personalized quote based on your specific project needs and to learn how the LlaVHHL-2 Llama Single Domain Antibody Library can enhance your research.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
