shRNA Adenovirus Serotype 5 (ΔE1/E3), pH1-(Armc5-shRNA-Seq1)(CAT#: AdV-SI3184WQ)

This product is a Armc5-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Armc5 gene encodes a member of the ARM (armadillo/beta-catenin-like repeat) superfamily. Mutations in this gene are associated with primary bilateral macronodular adrenal hyperplasia, which is also known as ACTH-independent macronodular adrenal hyperplasia 2. The expression of Armc5-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.