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NativeExtract™ Recombinant Full Length Human PKD2 Protein (Nanodisc, FLAG- & Strep-tagged) (CAT#: SYF-0426-CW76)

This product is recombinant Human PKD2 protein in native nanodisc form. The synthetic compound we developed can solubilize the PKD2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PKD2
  • Protein Length
  • Full length
  • Protein Class
  • Ion Channel
  • Molecular Weight
  • 109.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • The recombinant protein is constructed with FLAG Tag & Strep Tag at C-terminus.
  • Protein Format
  • Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • PKD2
  • Full Name
  • Polycystin 2, Transient Receptor Potential Cation Channel
  • Introduction
  • This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.
  • Alternative Names
  • PC2; PKD4; Pc-2; APKD2; TRPP2

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