Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsThe Ammonium transporter Rh type A (RHAG) is a membrane protein encoded by the RHAG gene in humans. In addition, RHAG has recently been designated as CD241 (Differentiated Cluster 241). Mutations in the RHAG gene result in increased stomata. RHAG is associated with the expression of the Ganges blood group antigen. RHAG may be part of an oligomeric complex that is possible to have a transport or channel function on the erythrocyte membrane. RHAG is in the process of ammonia transport on the erythrocyte membrane. It seems to play a role in monovalent cation transport.
| Basic Information of RHAG | |
| Protein Name | Ammonium transporter Rh type A |
| Gene Name | RHAG |
| Aliases | Erythrocyte membrane glycoprotein Rh50, Erythrocyte plasma membrane 50 kDa glycoprotein (Rh50A), Rhesus blood group family type A glycoprotein (Rh family type A glycoprotein, Rh type A glycoprotein), Rhesus blood group-associated ammonia channel, Rhesus blood group-associated glycoprotein, CD_antigen: CD241 |
| Organism | Homo sapiens (Human) |
| UniProt ID | Q02094 |
| Transmembrane Times | 12 |
| Length (aa) | 409 |
| Sequence | MRFTFPLMAIVLEIAMIVLFGLFVEYETDQTVLEQLNITKPTDMGIFFELYPLFQDVHVMIFVGFGFLMTFLKKYGFSSVGINLLVAALGLQWGTIVQGILQSQGQKFNIGIKNMINADFSAATVLISFGAVLGKTSPTQMLIMTILEIVFFAHNEYLVSEIFKASDIGASMTIHAFGAYFGLAVAGILYRSGLRKGHENEESAYYSDLFAMIGTLFLWMFWPSFNSAIAEPGDKQCRAIVNTYFSLAACVLTAFAFSSLVEHRGKLNMVHIQNATLAGGVAVGTCADMAIHPFGSMIIGSIAGMVSVLGYKFLTPLFTTKLRIHDTCGVHNLHGLPGVVGGLAGIVAVAMGASNTSMAMQAAALGSSIGTAVVGGLMTGLILKLPLWGQPSDQNCYDDSVYWKVPKTR |
The Rh blood group antigen (MIM 111700) is associated with human erythrocyte membrane proteins, approximately 30 kD, the so-called Rh30 polypeptide. The allogeneic glycosylation membrane protein, approximately 50 or 45 kD, Rh50 glycoprotein, binds to the Rh30 polypeptide under immunoprecipitation, with anti-r specific cells and polyclonal antibodies. The Rh antigen appears to be present in the multi-subunit complex of LW (MIM 111250), saccharin B (MIM 111740), CD47 (MIM 601028). In addition, RHAG may play a key role in the Rh50 glycoprotein.
Fig.1 The structure of Protein Ammonium transporter Rh type A.
These results show that epigenetic DNA methylation plays a key role in the increase in ambient temperature regulation of RHAG expression.
This article reveals that identification of significantly reduced surface expression of Rh/RhAG combined with flow cytometry provides an effective and rapid method for the direct evaluation of anchorage protein expression, which can be used to classify hereditary spherocytosis caused by the absence of anchor protein.
In this study, RhD has never been observed separately, strongly suggesting that its expression is completely dependent on the presence of transgenic human RHAG.
These results indicate that altered oocyte pH, current associated with RHAG or RHAG F65S expression and membrane potential may reflect different transport mechanisms.
It is concluded that, unlike humans with excessive water hyperplasia, in this standard group of Schnauzers, lipoblastosis is not caused by mutations in the gene-encoded RHAG, SLC4A1 or glutamine.
To obtain the soluble and functional target protein, the versatile Magic™ membrane protein production platform in Creative Biolabs enables many flexible options, from which you can always find a better match for your particular project. Besides, aided by our versatile Magic™ anti-membrane protein antibody discovery platform, we also provide customized anti-RHAG antibody development services.
Creative Biolabs' skillful scientists are glad to leverage our expertise and advanced technologies to help you with the member protein research. If you are interested, please feel free to contact us for more details.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
