Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsCyclic nucleotide-gated (CNG) channels, which belong to the superfamily of voltage-gated channels where the motion of the α-helix S6 controls gating in most of its members, mediate transduction in several sensory neurons. CNG channels are composed of 4 subunits, either of type alpha (CNGA1, CNGA2, CNGA3, CNGA4) or of type beta (CNGB1 and CNGB3) in mammals. These CNG channels use the free energy of cyclic nucleotides’ (CNs’) binding to open the pore, a process known as gating. Gating of CNG channels is initiated by the binding of CNs to the cyclic nucleotide-binding (CNB) domain and terminated with the opening of the gate located in the pore region, approximately some tens of Å apart. CNG channels play a vital role in signaling in the primary sensory cells of the vertebrate visual and olfactory systems.
In conclusion, CNG channels are important in the function of various sensory pathways such as vision and olfaction, as well as in other vital cellular functions including hormone release and chemotaxis. Here show the cyclic nucleotide-gated cation channel family members in human that you may be interested in.
Using our Magic™ membrane protein production platform, scientists at Creative Biolabs devote themselves to providing the preparation services of these targets in required formats using various strategies, including detergent micelles, proteoliposomes, nanodiscs, lipoparticles, polymers, with the stable cell line.
Moreover, our Magic™ membrane protein antibody discovery platform can also assist in discovering antibodies against these targets, even fully humanized antibodies, by various approaches including hybridoma technology, phage display technology, and etc. We also present DNA immunization service for anti-membrane protein antibody development. Please feel free to contact us for more information.
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