Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsAtypical chemokine receptor family (ACR) is a group of heptaspanning membrane receptors with seven transmembrane domains, which are structurally homologous to chemokine G-protein coupled receptors (GPCRs). ACR family is characterized by promiscuity of ligand binding and an apparent incapability to signal following ligand binding. ACR family comprises five receptors, antigen receptor for chemokines (DARC; atypical chemokine receptor 1), C-C chemokine receptor D6 (atypical chemokine receptor 2), CXCR7 (atypical chemokine receptor 3), CC-Chemokine receptors like 1 and 2 (CCRL1 and CCRL2; atypical chemokine receptor 4 and 5), which cover among them a wide range of chemokine ligands. ACRs are involved in a number of pathophysiological processes by regulating chemokine availability and function.
These receptors have proved to be important molecular players in health and disease. And the pivotal roles that ACRs play in the context of resolving inflammatory responses, underlines these receptors as potential therapeutic targets. Here, we give further detail information for several atypical chemokine receptors for your review.
Taking advantage of our MemDX™ membrane protein production platform, scientists in Creative Biolabs are focused on the preparation of these membrane proteins given above in required formats through different strategies, including detergent micelles, proteoliposomes, nanodiscs, MP-VLPs, polymers, with stable cell line.
What’s more, MemDX™ membrane protein antibody discovery platform at Creative Biolabs can be applied in developing antibodies against these targets, even fully humanized antibodies, by various approaches including hybridoma technology, phage display technology, and etc. We also present DNA immunization service for anti-membrane protein antibody development. Please feel free to contact us for more details.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
