Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsJunctophilin (JPH) family is a group of junctional membrane complex (JMC)-associated proteins existed in all excitable cells from striated muscle to neurons. Members of JPH family consist of specific protein domains. The family includes eight amino-terminal membrane occupation and recognition nexus (MORN) motifs separated by a joining region, followed by an alpha helix, divergent, and a C-terminal transmembrane motif that anchors the protein into the endoplasmic reticulum (ER) or sarcoplasmic reticulum (SR). JHPs are involved in the formation of JMCs which connect the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. And they provide a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
The link between these proteins and its critical roles in all excitable cells indicate the implications of junctophilins for human physiology and pathophysiology. JHPs hold the promise of novel therapeutic targets and molecular interventions for a number of these diseases. Below are some junctophilins that we have made detailed introductions for your review.
By utilizing our Magic™ membrane protein production platform, scientists at Creative Biolabs are experts in providing the preparation services of these targets in required formats using various strategies, including detergent micelles, proteoliposomes, nanodiscs, lipoparticles, polymers, with the stable cell line.
Moreover, our Magic™ membrane protein antibody discovery platform can also assist in discovering antibodies against these targets, even fully humanized antibodies, by various approaches including hybridoma technology, phage display technology, and etc. We also present DNA immunization service for anti-membrane protein antibody development. Please feel free to contact us for more information.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
