Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsInositol 1,4,5-trisphosphate receptor (InsP3R, IP3R) family is a group of membrane glycoprotein complexes functioning as an intracellular Ca2+ channel that mediates calcium release from the endoplasmic reticulum (ER), which is activated by inositol 1,4,5-trisphosphate (InsP3, IP3). IP3 receptors are very diverse among organisms and are involved in the regulation of epithelial secretion of electrolytes and fluid by the interaction with AHCYL1. They represent dominant second messengers inducing the release of Ca2+ from intracellular store sites. IP3 receptors are suggested to play a role in ER stress-induced cell apoptosis. Cytoplasmic calcium released from the ER induces cell apoptosis by the activation of CaM kinase II, eventually resulting in the activation of downstream apoptosis pathways.
IP3 receptors are also involved in some physiological processes such as fertilization, development, behavior, learning, and memory. And they are suggested to be important to the study of skeletal muscle development, health, and disease. We're concerned here with several IP3 receptors in human that you might be interested in.
Benefited by our MemDX™ membrane protein production platform, scientists at Creative Biolabs spare no effort to provide the protein preparation services of these membrane proteins mentioned above in required formats through different strategies, including detergent micelles, proteoliposomes, nanodiscs, MP-VLPs, polymers, with stable cell line.
Furthermore, MemDX™ membrane protein antibody discovery platform at Creative Biolabs can be used for developing antibodies against these targets, even fully humanized antibodies, by various approaches such as hybridoma technology, phage display technology, and etc. We also present DNA immunization service for anti-membrane protein antibody development. Please feel free to contact us for technical help.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
