Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsThe bestrophin family of proteins comprises four protein members containing bestrophin-1, bestrophin-2, bestrophin-3, and bestrophin-4, that are respectively encoded by evolutionarily related genes BEST1, BEST2, BEST3, and BEST4. Bestrophin, present in retinal pigment epithelial cells (RPE), is a basolateral plasma membrane protein with a molecular weight of 68 kDa. The proteins from this small family consisting of a highly conserved N-terminus with four to six transmembrane domains. Related research has shown that bestrophins are capable of forming calcium-activated chloride-ion channels in epithelial cells, however, they have been demonstrated highly permeable to bicarbonate ion transport in retinal tissue. In addition, bestrophins may play a role in the formation of chloride ion channels or the regulation of voltage-gated L-type calcium-ion channels.
Here, we present part of bestrophin transport proteins in humans including the following two different family members including bestrophin-1 and bestrophin-2.
Creative Biolabs is proud to offer the preparation of these targets in required formats using various strategies including detergent micelles, proteoliposomes, nanodiscs, MP-VLPs, polymers, stable cell line with the support of cutting-edge MemDX™ membrane protein production platform.
In addition, our MemDX™ membrane protein antibody discovery platform provides a good choice to assist our worldwide clients to discover antibodies against these targets, even fully humanized antibodies, by various approaches including hybridoma technology, phage display technology, etc. We also present DNA immunization service for anti-membrane protein antibody development. Please feel free to contact us for more information.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
