Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | 5-hydroxytryptamine receptor 1E |
| Gene Name | HTR1E |
| Uniprot | P28566 (Human) |
| Synonym | 5-HT1E; 5-HT-1E; 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled; S31; serotonin receptor 1E |
| Background | 5-hydroxytryptamine receptor 1E, alternatively known as serotonin receptor 1E, is one of the subtypes for serotonin receptor (5-HT receptor) and in human is encoded by HTR1E gene. HTR1E is highly expressed in the human brain. Specifically, it was detected in the adventitial layer of cerebral arteries but not in the microvasculature, venous tissue or other brain arteries. The presence of HTR1E in brain areas involved in memory suggests that they might play a role in memory. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX349 | NativeExtract™ Human HTR1E Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| MPX3469K | MemDX™ Membrane Protein Human HTR1E Expressed in vitro E.coli expression system, Full Length | E.coli cell-free | Full length | Detergent |
| MP0531X | MemDX™ Membrane Protein Human HTR1E (5-hydroxytryptamine receptor 1E) for Antibody Discovery | Wheat germ cell-free | Full length | Liposome |
| Please for more products or customization | ||||
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Creative Biolabs offers genomic sequencing and bioinformatics services. Employing contemporary next-generation sequencing (NGS) methodologies represents a powerful approach for the detection of mutational events or genetic polymorphisms within the HTR1E locus. Subsequently, the application of sophisticated bioinformatics pipelines facilitates the interrogation of these resultant sequence data, enabling the in-silico prediction of the functional consequences stemming from the identified genetic alterations. This analytical strategy may offer critical insights into the potential phenotypic ramifications associated with variations in this specific gene.
Creative Biolabs offers viral vectors development services. The transduction of target cell populations with the HTR1E gene can be effectively achieved through the utilization of viral vectors, with adeno-associated virus (AAV) and lentivirus representing prominent examples within this methodology. Notably, AAV vectors present distinct advantages, primarily attributable to their diminished immunogenic profile. Furthermore, these vectors exhibit a broad tropism, demonstrating the capacity to transduce both actively dividing and quiescent cellular populations. This characteristic may render AAV-mediated gene delivery particularly efficacious in specific therapeutic or research contexts.
Creative Biolabs offers non-viral vectors development services. The development of non-viral vectors, encompassing entities such as plasmid DNA constructs or engineered nanoparticles, represents an alternative strategy for the delivery of genetic material. These methodologies may proffer enhanced safety profiles and potentially greater cost-effectiveness in comparison to viral vector systems. However, it is pertinent to note that such non-viral approaches might exhibit comparatively reduced transduction efficiencies, a factor that warrants careful consideration in the design and implementation of gene transfer experiments. Perhaps further optimization of these non-viral systems could mitigate this limitation.
Creative Biolabs offers comprehensive and innovative services to drive the development of HTR1E cell therapy. Please for more services.
Creative Biolabs offers immune evasion strategies development services. The engineering of cellular systems to express immunosuppressive molecules, such as programmed death-ligand 1 (PD-L1) or cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), represents a potential avenue for modulating immune responses. Furthermore, the co-delivery of immune checkpoint inhibitors in conjunction with such engineered cells may serve to augment immune tolerance mechanisms and, consequently, improve overall therapeutic outcomes in specific contexts.
Creative Biolabs offers secretome analysis services. The analysis of secreted factors emanating from HTR1E-modified cellular systems, which may include cytokines and growth factors, can be effectively undertaken through the implementation of enzyme-linked immunosorbent assays (ELISA) or multiplex cytokine assays. The resultant quantitative data may facilitate the identification of potential biomarkers suitable for therapeutic monitoring paradigms. These investigations could yield valuable insights into the broader biological impact of HTR1E modulation.
Creative Biolabs has worked all out in the field of membrane protein preparation to support membrane protein studies. Our experienced scientists will spare no effort to advance their research and programs of membrane protein preparation. Please feel free to for more details.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
