Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsUrea transporters (UTs), also known as solute carrier family 14 (SLC14), are a family of membrane proteins that transport urea molecules across cell membranes and play important roles in a variety of physiological processes, such as mediating the rapid and passive diffusion of urea down its concentration gradient. It has been reported that UTs are expressed in a wide variety of tissues, but their function is best understood in the kidney where they contribute to maintaining the high interstitial urea concentration necessary to limit the rate of water loss. In mammals, two types of urea transport proteins, UT-A and UT-B, have been identified. Particularly, the UT-A proteins are important for renal urea handling and are produced by alternative splicing of the SLC14A2 gene. What’s more, studies have shown that the majority of the variants of SLC14 transporters have 10 transmembrane domains, with a glycosylated extracellular loop at TM5/6, and intracellular C- and N-termini.
Here, we have described in detail of members of the SLC14, including SLC14A1 and SLC14A2. To learn more detailed information, please click the links below.
With the help of advanced MemDX™ membrane protein production platform, Creative Biolabs is committed to offering various target membrane protein products in required formats using various strategies, such as detergent micelles, proteoliposomes, nanodiscs, MP-VLPs, polymers, stable cell line.
In addition, our MemDX™ membrane protein antibody discovery platform can help to discover antibodies against these targets, even fully humanized antibodies, by various approaches such as hybridoma technology, phage display technology. We also present DNA immunization service for anti-membrane protein antibody development. To get more detailed information, please feel free to contact us.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
