Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsCorticotropin-releasing factor receptors (CRFRs), also known as corticotropin-releasing hormone receptors (CRHRs), are a G protein-coupled receptor family that binds corticotropin-releasing hormone (CRH). Currently, there are two receptors in the family, termed CRHR1 and CRHR2, each encoded by a separate gene. Both of them are extensively distributed in the central nervous system (CNS) and the periphery. Studies have shown that CRHRs are important mediators in stress response. Cells in the anterior lobe of the pituitary gland known as corticotropes express the receptors and will secrete adrenocorticotropic hormone (ACTH) when stimulated. Moreover, it is recognized that the two subtypes of CRF receptor display quite different pharmacological profiles. To date, the expression of at least eight variants of CRFR1 mRNA (a, b, c, d, e, f, g and h) and three variants of CRFR2 mRNA (a, b, and c) has been detected and these alternative splicings were found to be regulated by diverse physiological and pathological factors in humans.
Here, we have listed all the members of the corticotropin-releasing factor receptor family, including corticotropin-releasing factor receptor 1 and corticotropin-releasing factor receptor 2. To learn more information about CRHR1 and CRHR2, please click the links below.
Aided by our advanced MemDX™ membrane protein production platform, Creative Biolabs is confident in offering diverse target membrane protein products in required formats using various strategies, such as detergent micelles, proteoliposomes, nanodiscs, MP-VLPs, polymers, stable cell line.
Meanwhile, our MemDX™ membrane protein antibody discovery platform can help to discover antibodies against these targets, even fully humanized antibodies, by various approaches such as hybridoma technology and phage display technology. We also present DNA immunization service for anti-membrane protein antibody development. To get more detailed information, please feel free to contact us.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
