Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
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HighlightsPotassium voltage-gated channel subfamily A belongs to the voltage-gated potassium channels (VGKCs) which are transmembrane channels specific for potassium and sensitive to voltage changes in the cell's membrane potential, primarily in the brain and the central nervous system. Generally, channel properties depend on the type of alpha subunits that are part of the channel. Studies have shown that they can form functional homotetrameric channels and heterotetrameric channels that contain different proportions of the VGKC subfamily A, such as KCNA1, KCNA2, KCNA4, and possibly other family members as well. During the past years, a broad range of physiological processes which depend on voltage-gated ion channels VGICs has been determined, including cellular signaling, control of muscle contraction, and ion homeostasis in non-excitable cells. What’s more, it has been reported that the VGKC subfamily A also contributes to the regulation of the membrane potential and nerve signaling, and prevents neuronal hyperexcitability.
Here, we have described in details of members of the VGKC subfamily A, which including but not limited to potassium voltage-gated channel subfamily A member 1, potassium voltage-gated channel subfamily A member 2, and potassium voltage-gated channel subfamily A member 3. To learn more detailed information, please click the links below.
Aided by our advanced Magic™ membrane protein production platform, Creative Biolabs is confident in offering diverse target membrane protein products in required formats using various strategies, such as detergent micelles, proteoliposomes, nanodiscs, lipoparticles, polymers, stable cell line
Meanwhile, our Magic™ membrane protein antibody discovery platform can help to discover antibodies against these targets, even fully humanized antibodies, by various approaches such as hybridoma technology, phage display technology. We also present DNA immunization service for anti-membrane protein antibody development. To get more detailed information, please feel free to contact us.
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