Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsSolute carrier family 11 (SLC11), also known as natural resistance-associated macrophage proteins (NRAMPs), belongs to the “Amino acid-Polyamine-organoCation (APC)” superfamily, containing Na+- and H+-coupled secondary transporters and symporters, some of which are particularly well characterized, such as LeuT. SLC11 is composed of two transporters (SLC11A1/NRAMP1 and SLC11A2/NRAMP2) which both have 12 transmembrane regions and cytoplasmic N- and C- termini. Studies have suggested that SLC11A1 is expressed in the phagosomes of macrophages and it plays an essential role in host defense against pathogens. What’s more, it is also involved in the antimicrobial action in macrophages, although its precise mechanism is undefined. Whereas, SLC11A2 is more widely expressed and appears to assist in divalent cation assimilation from the diet, as well as in phagocytotic cells.
Here, we have described in detail of members of the SLC11 family, including SLC11A1and SLC11A2. To learn more detailed information, please click the links below.
With the help of our advanced MemDX™ membrane protein production platform, Creative Biolabs is committed to offering various target membrane protein products in required formats using various strategies, such as detergent micelles, proteoliposomes, nanodiscs, MP-VLPs, polymers, stable cell line.
Furthermore, our MemDX™ membrane protein antibody discovery platform can help to discover antibodies against these targets, even fully humanized antibodies, by various approaches such as hybridoma technology, phage display technology. We also present DNA immunization service for anti-membrane protein antibody development. To get more detailed information, please feel free to contact us.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
