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Anti-Inflammation Diseases-Specific Antibody Discovery from Premade Phage Displayed Antibody Library

As a leading service provider in the field of antibody production and engineering, Creative Biolabs has constructed a comprehensive portfolio of high-quality phage display libraries to offer custom-designed premade antibody library screening services for global researchers. For recent years, our scientists are devoted to developing novel anti-disease-specific target antibodies from our premade phage displayed antibody libraries, which including but not limited to anti-inflammation disease-specific antibodies.

Anti-Inflammation Diseases-Specific Antibody

Human inflammatory diseases, including rheumatoid arthritis (RA) and other related or non-related arthritides, skin diseases, are among some of the most debilitating conditions described and they inflict varying degrees of functional impairment and may be long-lasting, causing chronic pain. Studies have shown that inflammatory cytokines are key regulators of immune responses. Persistent and excessive production of inflammatory cytokines underscores the development of autoimmune diseases. Therefore, the development of therapeutic antibodies to neutralize inflammatory cytokines or antagonize their receptor function has been considered as a useful therapeutic strategy to treat autoimmune diseases.

Anti-Inflammation Diseases-Specific Antibody Discovery from Premade Phage Displayed Antibody LibraryFig.1 Approaches for the development of therapeutic antibodies. (Lu, 2020)

Premade Phage Displayed Antibody Library Screening for Anti-Inflammation Diseases-Specific Antibody

During the past years, antibodies have become the predominant treatment modality for various diseases. Particularly, major technological advances have made the discovery and development of antibody therapies quicker and more efficient. With advanced technology platforms and rich experience, Creative Biolabs has constructed immune, naïve, and synthetic premade antibody libraries with large library capacity from 107 to over 1012. Our scientists are confident in utilizing the novel biopanning strategies to select high-affinity binders to recognize specific targets. We are pleased to offer the best service and the most qualified products to satisfy each demand from our customers. Premade phage displayed antibody libraries available at Creative Biolabs include:

Libraries Library ID Display Technology Library Format Species Library Size
Phage display human scFv libraries HuScL-2 Phage Display scFv Human 1.42×109
HuScL-4 Phage Display scFv Human 2.0×109
HuScL-6 Phage Display scFv Human 1.0×1011
HuScL-7 Phage Display scFv Human 1.1×1010
Phage display human Fab libraries HuFabL-4 Phage Display Fab Human 1.9×1010
HuFabL-5 Phage Display Fab Human 1.1×1010
HuFabssL-1 Phage Display Fab Human 1.8×1010


Creative Biolabs also provides antibody discovery services for different types of targets to suit a variety of applications:


Advantages of Our Service


Creative Biolabs is dedicated to the development and application of phage display technology. With years of experience, our scientists have developed several phage displayed antibody libraries to boost our global customers' research and project goals. We are pleased to use our extensive experience and advanced platform to screen novel antibodies against specific targets to satisfy each demand from our customers. For more detailed information, please contact us by sending E-mail and our team will get back to you as soon as possible.

Reference

  1. Lu, R.M., et al. Development of therapeutic antibodies for the treatment of diseases. Journal of biomedical science. 2020, 27(1), pp.1-30.

All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

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