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Anti-Infectious Diseases-Specific Antibody Discovery from Premade Phage Displayed Antibody Library

Creative Biolabs offers the world-leading custom premade antibody library screening service with the most advanced phage display techniques and years of experience. Our technical experts are looking forward to designing a strategy of anti-infectious diseases-specific antibody discovery to meet your project needs.

Anti-Infectious Diseases-Specific Antibody

Antibodies, an important component in host immune responses to viral pathogens, have been widely used for the treatment of numerous diseases, including cancer, inflammatory disorders, and infectious diseases. Compared to traditional small molecules, antibodies are highly specific, allowing for selective targeting of pathogens, without disturbing the natural microbiota. Generally, antibodies targeting pathogens can exhibit multiple mechanisms of action, including bactericidal activities, such as complement-mediated or opsonophagocytic killing, as well as more specialized anti-virulence functions. Under this condition, antibodies have the potential to reduce the spread of antibiotic resistance and, since the mechanisms of action are complimentary, antibodies and antibiotics often exhibit additive or synergistic effects when co-administered.

Anti-Infectious Diseases-Specific Antibody Discovery from Premade Phage Displayed Antibody LibraryFig.1 Novel protectives mechanisms used by anti-infective antibodies in development. (Wagner, 2018)

Premade Phage Displayed Antibody Library Screening for Anti-Infectious Diseases-Specific Antibody

Facilitated by numerous antibody discovery technologies, including human immune repertoire profiling, polyclonal immunoglobulin, target agnostic, and structure-based computational antibody design, a suite of exciting new antibodies for infectious diseases have been developed during the past years. As a leading service provider in the field of antibody production, Creative Biolabs has constructed multiple both naïve and synthetic libraries with large capacity and diversity, which enables us to offer comprehensive premade antibody library screening services to help global researchers discover ideal binders against specific targets. Our professional scientists are happy to aid you to find the most suitable option to make your project a success. Our premade phage displayed antibody libraries include:

Libraries Library ID Display Technology Library Format Species Library Size
Phage display human scFv libraries HuScL-2 Phage Display scFv Human 1.42×109
HuScL-4 Phage Display scFv Human 2.0×109
HuScL-6 Phage Display scFv Human 1.0×1011
HuScL-7 Phage Display scFv Human 1.1×1010
Phage display human Fab libraries HuFabL-4 Phage Display Fab Human 1.9×1010
HuFabL-5 Phage Display Fab Human 1.1×1010
HuFabssL-1 Phage Display Fab Human 1.8×1010


Creative Biolabs also provides antibody discovery services for different types of targets to suit a variety of applications:


Advantages of Our Service


Creative Biolabs is capable of offering the best premade antibody screening service to satisfy your specific needs. With rich experience in phage display, we are confident in freeing up your time for core work and projects. If you are interested in our service, please contact us by sending E-mail and our team will get back to you as soon as possible.

Reference

  1. Wagner, E.K. and Maynard, J.A. Engineering therapeutic antibodies to combat infectious diseases. Current opinion in chemical engineering. 2018, 19, pp.131-141.

All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

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