EpCAM

Epithelial cell adhesion molecule (EpCAM), also called DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1, is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation and differentiation. This protein can be used as a potential prognostic marker and as a potential target for immunotherapeutic strategies. EpCAM is associated with a lot of cancers including colon cancer, breast cancer, ovarian cancer, renal cancer (RCC), head and neck squamous cell carcinoma (HNSCC) and esophagus squamous cell carcinomas.

Associated Disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC181 T cell Third ~8kb Retroviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-MZ151 T cell First M13-57 ~8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-MZ152 T cell Second M13-57 ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ153 T cell Second M13-57 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC664 Lentivirus Second scFv-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC846 M13-57 Lentivirus First scFv (M13-57)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC847 M13-57 Lentivirus Second scFv (M13-57)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC848 M13-57 Lentivirus Second scFv (M13-57)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
CONTACT US

USA
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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
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Tel: 44-207-048-3343

Distributors

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