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ZFYVE19

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WJ2169 Anti-ZFYVE19 (4D5-2D11) h(41BB-CD3ζ) CAR, pCDCAR1 Human 4D5-2D11 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ2170 Anti-ZFYVE19 (3G4-2B11) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3G4-2B11 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ2171 Anti-ZFYVE19 (CBWJZ-086) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJZ-086 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ2172 Anti-ZFYVE19 (CBWJZ-085) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJZ-085 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4461 Anti-ZFYVE19 (4D5-2D11) h(CD28-CD3ζ) CAR, pCDCAR1 Human 4D5-2D11 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4462 Anti-ZFYVE19 (3G4-2B11) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3G4-2B11 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4463 Anti-ZFYVE19 (CBWJZ-086) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBWJZ-086 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4464 Anti-ZFYVE19 (CBWJZ-085) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBWJZ-085 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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