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CEA

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (Cluster of Differentiation 66e), is a protein encoded by CEACAM5 gene in human. Carcinoembryonic antigen (CEA) describes a set of highly related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Therefore, CEA is usually present only at very low levels in the blood of healthy adults. However, the serum levels are raised in some types of cancer, so that CEA usually act as a tumor marker in clinical test. CEA are glycosyl phosphatidyl inositol (GPI) cell-surface-anchored glycoproteins whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.

Associated Disease
  • CAR Vector Products
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  • CAR Viral Particles
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CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-T-1-M314-G Anti-CEA scFv h(FcεRIγ) CART, pCDCAR1 Human BW431/26 Human scFv-FcεRIγ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-1-M314-Z Anti-CEA scFv h(CD3ζ) CART, pCDCAR1 Human BW431/26 Human scFv-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-M314-2G Anti-CEA scFv h(CD28-FcεRIγ) CART, pCDCAR1 Human BW431/26 Human scFv-CD28-FcεRIγ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-M314-2Z Anti-CEA scFv h(CD28-CD3ζ) CART, pCDCAR1 Human BW431/26 Human scFv-CD28-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-M314-4G Anti-CEA scFv h(CD4-FcεRIγ) CART, pCDCAR1 Human BW431/26 Human scFv-CD4-FcεRIγ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-M314-4Z Anti-CEA scFv h(CD4-CD3ζ) CART, pCDCAR1 Human BW431/26 Human scFv-CD4-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-M314-8Z Anti-CEA scFv h(CD8-CD3ζ) CART, pCDCAR1 Human BW431/26 Human scFv-CD8-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-M314-BZ Anti-CEA scFv h(41BB-CD3ζ) CART, pCDCAR1 Human BW431/26 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-M314-CZ Anti-CEA scFv h(b2c-CD3ζ) CART, pCDCAR1 Human BW431/26 Human scFv-b2c-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-3-M314-2BZ Anti-CEA scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 Human BW431/26 Human scFv-CD28-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-3-M314-2XZ Anti-CEA scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 Human BW431/26 Human scFv-CD28-OX40-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-1-M314-2 Anti-CEA scFv h(CD28) CART, pCDCAR1 Human BW431/26 Human scFv-CD28 Lentiviral T cell   Inquiry
  Datasheet
CAR-LC019 Anti-CEA h(CD28-CD3ζ) CAR, pCDCAR1 Human Arcitumomab Mouse scFv-CD28-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-LC020 Anti-CEA h(CD3ζ-CD28) CAR, pCDCAR1 Human Labetuzumab Human scFv-CD3ζ-CD28 Retroviral T cell   Inquiry
  Datasheet
CAR-LC375 Anti-CEACAM5 h(CD28-CD3ζ, GITR) Armoured CAR, pCDCAR1 Human Labetuzumab Human scFv-CD28-CD3ζ-GITR Retroviral T cell   Inquiry
  Datasheet
CAR-MZ087 Anti-CEA (SCA431) h(CD3ζ) CAR, pCDCAR1 Mouse SCA431 Mouse scFv-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-MZ088 Anti-CEA (SCA431) h(CD28-CD3ζ) CAR, Pcdcar1 Mouse SCA431 Mouse scFv-CD28-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-MZ089 Anti-CEA (SCA431) h(OX40-CD3ζ) CAR, pCDCAR1 Mouse SCA431 Mouse scFv-OX40-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-MZ090 Anti-CEA (SCA431) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Mouse SCA431 Mouse scFv-CD28-OX40-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-MZ105 Anti-CEA (MFE23) h(CD3ζ) CAR, pCDCAR1 Human MFE23 Mouse scFv-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-MZ106 Anti-CEA (MFE23) h(CD28-CD3ζ) CAR, pCDCAR1 Human MFE23 Mouse scFv-CD28-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-MZ107 Anti-CEA (MFE23) h(41BB-CD3ζ) CAR, pCDCAR1 Human MFE23 Mouse scFv-41BB-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-MZ108 Anti-CEA (MFE23) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human MFE23 Mouse scFv-CD28-41BB-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-LC368 Anti-CEACAM5 h(CD3ζ, CD80, 41BBL) Armoured CAR, pCDCAR1 Human Arcitumomab Mouse scFv-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-MZ170 Anti-CEA (C2-45) h(CD3ζ) CAR, pCDCAR1 Human C2-45 Human scFv-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-MZ171 Anti-CEA (C2-45) h(CD28-CD3ζ) CAR, pCDCAR1 Human C2-45 Human scFv-CD28-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-MZ172 Anti-CEA (C2-45) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human C2-45 Human scFv-CD28-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-MZ144 Anti-CEA (F11-39) h(CD28-CD3ζ) CAR, pCDCAR1 Human F11-39 Mouse scFv-CD28-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-MZ145 Anti-CEA (F11-39) h(41BB-CD3ζ) CAR, pCDCAR1 Human F11-39 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-MZ146 Anti-CEA (F11-39) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human F11-39 Mouse scFv-CD28-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-YF027 Anti-CEA (C2-45) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human C2-45 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YF028 Anti-CEA (M5A) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human M5A Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YF029 Anti-CEA (M5A) h(CD28-CD3ζ) CAR, pCDCAR1 Human M5A Human scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YF030 Anti-CEA (hMN-14) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human hMN-14 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YF031 Anti-CEA (hMN-14) h(CD28-CD3ζ) CAR, pCDCAR1 Human hMN-14 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-MZ042 Anti-CEA (BW431/26) h(CD3ζ-OX40) CAR, pCDCAR1 Human BW431/26 Human scFv-CD3ζ-OX40 Retroviral T cell   Inquiry
  Datasheet
CAR-YF121 Anti-CEA (CBL-YF040) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF040 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YF122 Anti-CEA (CBL-YF040) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF040 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-ZP041 Anti-CEA (hMN14) h(CD28-CD3ζ) CAR, pCDCAR1 Human hMN14 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet
CAR-YF149 Anti-CEA (G4S) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human G4S Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Inquiry
  Datasheet

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