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CEA

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (Cluster of Differentiation 66e), is a protein encoded by CEACAM5 gene in human. Carcinoembryonic antigen (CEA) describes a set of highly related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Therefore, CEA is usually present only at very low levels in the blood of healthy adults. However, the serum levels are raised in some types of cancer, so that CEA usually act as a tumor marker in clinical test. CEA are glycosyl phosphatidyl inositol (GPI) cell-surface-anchored glycoproteins whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.

Associated Disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type 		Generation Antibody
Clone 		Vector
Length 		Vector
Type 		Vector Design Antibody
Host 		Data
sheet		 Price
CAR-LC019 T cell Second Arcitumomab ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-LC020 T cell Second Labetuzumab ~8kb Retroviral scFv-CD3ζ-CD28 Human Inquiry
CAR-LC368 T cell First Arcitumomab ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-LC375 T cell Second Labetuzumab ~8kb Retroviral scFv-CD28-CD3ζ-GITR Human Inquiry
CAR-MZ042 T cell Second BW431/26 ~8kb Retroviral scFv-CD3ζ-OX40 Human Inquiry
CAR-MZ087 T cell First SCA431 ~8kb Retroviral scFv-CD3ζ Mouse Inquiry
CAR-MZ088 T cell Second SCA431 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ089 T cell Second SCA431 ~8kb Retroviral scFv-OX40-CD3ζ Mouse Inquiry
CAR-MZ090 T cell Third SCA431 ~8kb Retroviral scFv-CD28-OX40-CD3ζ Mouse Inquiry
CAR-MZ105 T cell First MFE23 ~8kb Retroviral scFv-CD3ζ Mouse Inquiry
CAR-MZ106 T cell Second MFE23 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ107 T cell Second MFE23 ~8kb Retroviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ108 T cell Third MFE23 ~8kb Retroviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-MZ144 T cell Second F11-39 ~8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ145 T cell Second F11-39 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ146 T cell Third F11-39 ~8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-MZ170 T cell First C2-45 ~8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-MZ171 T cell Second C2-45 ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ172 T cell Third C2-45 ~8kb Lentiviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-T-1-M314-2 T cell First BW431/26 8kb Lentiviral scFv-CD28 Human Inquiry
CAR-T-1-M314-G T cell First BW431/26 8kb Lentiviral scFv-FcεRIγ Human Inquiry
CAR-T-1-M314-Z T cell First BW431/26 8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-T-2-M314-2G T cell Second BW431/26 8kb Lentiviral scFv-CD28-FcεRIγ Human Inquiry
CAR-T-2-M314-2Z T cell Second BW431/26 8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-T-2-M314-4G T cell Second BW431/26 8kb Lentiviral scFv-CD4-FcεRIγ Human Inquiry
CAR-T-2-M314-4Z T cell Second BW431/26 8kb Lentiviral scFv-CD4-CD3ζ Human Inquiry
CAR-T-2-M314-8Z T cell Second BW431/26 8kb Lentiviral scFv-CD8-CD3ζ Human Inquiry
CAR-T-2-M314-BZ T cell Second BW431/26 8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-T-2-M314-CZ T cell Second BW431/26 8kb Lentiviral scFv-b2c-CD3ζ Human Inquiry
CAR-T-3-M314-2BZ T cell Third BW431/26 8kb Lentiviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-T-3-M314-2XZ T cell Third BW431/26 8kb Lentiviral scFv-CD28-OX40-CD3ζ Human Inquiry

TCR Vector Products Product list:

Catalog Target Target
Species 		Antibody
Clone 		scFv-Host
Animal 		Vector
length 		Vector
Type 		Epitope Format HLA Data
sheet		 Price
TCR-C035Z CEA Human Mouse ~8kb Lentiviral IMIGVLVGV Affinity enhanced HLA-A*0201 Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone 		Packaging
System 		Generation Gene
Construct 		Promotor Packaging
Cell 		Titer Data
sheet		 Price
VP-CAR-LC145 BW431/26 Lentivirus First scFv (BW431/26)-CD28 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC146 BW431/26 Lentivirus First scFv (BW431/26)-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC147 BW431/26 Lentivirus First scFv (BW431/26)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC148 BW431/26 Lentivirus Second scFv (BW431/26)-CD28-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC149 BW431/26 Lentivirus Second scFv (BW431/26)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC150 BW431/26 Lentivirus Second scFv (BW431/26)-CD4-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC151 BW431/26 Lentivirus Second scFv (BW431/26)-CD4-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC152 BW431/26 Lentivirus Second scFv (BW431/26)-CD8-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC153 BW431/26 Lentivirus Second scFv (BW431/26)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC154 BW431/26 Lentivirus Second scFv (BW431/26)-b2c-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC155 BW431/26 Lentivirus Third scFv (BW431/26)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC156 BW431/26 Lentivirus Third scFv (BW431/26)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC716 MN14 Lentivirus Second scFv (MN14)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC763 BW431/26 Lentivirus Second scFv (BW431/26)-CD3ζ-OX40 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC795 SCA431 Lentivirus First scFv (SCA431)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC796 SCA431 Lentivirus Second scFv (SCA431)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC797 SCA431 Lentivirus Second scFv (SCA431)-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC798 SCA431 Lentivirus Third scFv (SCA431)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC804 MFE23 Lentivirus First scFv (MFE23)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC805 MFE23 Lentivirus Second scFv (MFE23)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC806 MFE23 Lentivirus Second scFv (MFE23)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC807 MFE23 Lentivirus Third scFv (MFE23)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC841 F11-39 Lentivirus Second scFv (F11-39)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC842 F11-39 Lentivirus Second scFv (F11-39)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC843 F11-39 Lentivirus Third scFv (F11-39)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC864 C2-45 Lentivirus First scFv (C2-45)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC865 C2-45 Lentivirus Second scFv (C2-45)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC866 C2-45 Lentivirus Third scFv (C2-45)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry

TCR Viral Particles Product list:

Catalog Target
Species 		Antibody
Clone 		scFv-Host
Animal 		Packaging
System 		Epitope Format Titer Data
sheet		 Price
VP-TCR-C036 Human Mouse Lentivirus IMIGVLVGV Affinity enhanced TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C037 Human Mouse Lentivirus IMIGVLVGV Codon optimized TCR > 10⁷ IFU/ml Inquiry
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