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Tyrosine-protein kinase transmembrane receptor ROR1, also called neurotrophic tyrosine kinase receptor-related 1 (NTRKR1), belongs to the receptor tyrosine kinase-like orphan receptor (ROR) subfamily. It is a type I membrane protein, which is regulating neurite growth in the central nervous system. ROR1 is playing a functional role in the activity of ovarian cancer cells, and associated with B-cell chronic lymphocytic leukaemia.
Associated Disease
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| CAR-MV-01LX396 | Anti-ROR1 (XBR1-402) h(41BB-CD3ζ) CAR, pMMLV | Human | XBR1-402 | Rabbit | scFv-41BB-CD3ζ | Recombinant Moloney murine leukemia virus (MMLV) retroviral vector | T cell | ||
| CAR-MV-01LX397 | Anti-ROR1 (ERR1-TOP43) h(41BB-CD3ζ) CAR, pMMLV | Human | ERR1-TOP43 | Rabbit | scFv-41BB-CD3ζ | Recombinant Moloney murine leukemia virus (MMLV) retroviral vector | T cell | ||
| CAR-MV-01LX401 | Anti-ROR1 (V331) h(41BB-CD3ζ) CAR, pMMLV | Human | V331 | human | scFv-41BB-CD3ζ | Recombinant Moloney murine leukemia virus (MMLV) retroviral vector | T cell | ||
| CAR-SB-02LX149 | Anti-ROR1 (ERR1-TOP43) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 | Human | ERR1-TOP43 | Rabbit | scFv-CD28-41BB-CD3ζ | Sleeping Beauty (SB) transposon | T cell | ||
| CAR-SB-02LX157 | Anti-ROR1 (4A5) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 | Human | 4A5 | Humanized | scFv-CD28-41BB-CD3ζ | Sleeping Beauty (SB) transposon | T cell | ||
| XS-0622-ZP3213 | Anti-ROR1 h(VHH1-VHH2-CD28-CD3ζ) Biepitopic CAR, pCDCAR1 | Human | VHH1-VHH2-CD28-CD3ζ | Lentiviral vector | T Cell | ||||
| XS-0722-YF59 | TS-Fluc Anti-Human ROR1 scFv (R11) CD28-CD3ζ CAR, pCDCAR1 | Human | R11 | Rabbit | 7H-YB-Fluc-EF1a-scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| XS-0722-YF60 | TS-Fluc Anti-Human ROR1 scFv (R12) CD28-CD3ζ CAR, pCDCAR1 | Human | R12 | Rabbit | 7H-YB-Fluc-EF1a-scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| XS-0722-YF119 | TS-Fluc Anti-Human ROR1 scFv (R11) 4-1BB-CD3ζ CAR, pCDCAR1 | Human | R11 | Rabbit | 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
| XS-0722-YF120 | TS-Fluc Anti-Human ROR1 scFv (R12) 4-1BB-CD3ζ CAR, pCDCAR1 | Human | R12 | Rabbit | 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
| XS-0722-YF179 | TS-Fluc Anti-Human ROR1 scFv (R11) CD28-4-1BB-CD3ζ CAR, pCDCAR1 | Human | R11 | Rabbit | 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ | Lentiviral vector | T cell | ||
| XS-0722-YF180 | TS-Fluc Anti-Human ROR1 scFv (R12) CD28-4-1BB-CD3ζ CAR, pCDCAR1 | Human | R12 | Rabbit | 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ | Lentiviral vector | T cell | ||
| XS-0722-YF239 | TS-IL15 SA Anti-Human ROR1 scFv (R11) CD28-CD3ζ CAR, pCDCAR1 | Human | R11 | Rabbit | 7H-YB-IL15 SA-EF1a-scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| XS-0722-YF240 | TS-IL15 SA Anti-Human ROR1 scFv (R12) CD28-CD3ζ CAR, pCDCAR1 | Human | R12 | Rabbit | 7H-YB-IL15 SA-EF1a-scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| XS-0722-YF299 | TS-IL15 SA Anti-Human ROR1 scFv (R11) 4-1BB-CD3ζ CAR, pCDCAR1 | Human | R11 | Rabbit | 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
| XS-0722-YF300 | TS-IL15 SA Anti-Human ROR1 scFv (R12) 4-1BB-CD3ζ CAR, pCDCAR1 | Human | R12 | Rabbit | 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
| XS-0722-YF359 | TS-IL15 SA Anti-Human ROR1 scFv (R11) CD28-4-1BB-CD3ζ CAR, pCDCAR1 | Human | R11 | Rabbit | 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ | Lentiviral vector | T cell | ||
| XS-0722-YF360 | TS-IL15 SA Anti-Human ROR1 scFv (R12) CD28-4-1BB-CD3ζ CAR, pCDCAR1 | Human | R12 | Rabbit | 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ | Lentiviral vector | T cell | ||
| XS-0722-YF419 | TS-NKG2DL Anti-hCD3 and Anti-Human ROR1 scFv (R11) CD28-CD3ζ CAR, pCDCAR1 | Human | R11 | Rabbit | 7H-YB-NKG2DL Anti-hCD3 and (OKT3 scFv-NKG2D ECD)-EF1a-scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| XS-0722-YF420 | TS-NKG2DL Anti-hCD3 and Anti-Human ROR1 scFv (R12) CD28-CD3ζ CAR, pCDCAR1 | Human | R12 | Rabbit | 7H-YB-NKG2DL Anti-hCD3 and (OKT3 scFv-NKG2D ECD)-EF1a-scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| XS-0823-LX87 | Anti-hROR1 (12) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector | Human | 12 | Adenoviral vectors |
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