CD133

CD133 antigen also known as prominin-1 is a glycoprotein that in humans is encoded by the PROM1 gene. It is a member of pentaspan transmembrane glycoproteins (5-transmembrane, 5-TM), which specifically localize to cellular protrusions. While the precise function of CD133 remains unknown, it has been proposed to act as an organizer of cell membrane topology. The pentaspan membrane glycoprotein CD133 marks lineage-specific cancer progenitor cells and is associated with poor prognosis in a number of tumor types. Despite its utility as a cancer progenitor cell marker, CD133 protein regulation and molecular function remain poorly understood.


CAR Vector Products Product list:

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Vector
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Type
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Data
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Price
CAR-LC241 T cell Second AC133 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry

CAR Viral Particles Product list:

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Price
VP-CAR-LC713 Lentivirus Second scFv-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
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