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BCAM

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This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ0043 Anti-BCAM (G253) h(41BB-CD3ζ) CAR, pCDCAR1 Human G253 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3467 Anti-BCAM (G253) h(CD28-CD3ζ) CAR, pCDCAR1 Human G253 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2616 Anti-BCAM (G418) h(41BB-CD3ζ) CAR, pCDCAR1 Human G418 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5869 Anti-BCAM (G418) h(CD28-CD3ζ) CAR, pCDCAR1 Human G418 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ0027 Anti-BCAM (BRIC221) h(41BB-CD3ζ) CAR, pCDCAR1 Human BRIC221 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ0028 Anti-BCAM (CBWJC-0378) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJC-0378 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ0029 Anti-BCAM (CBWJC-0379) h(41BB-CD3ζ) CAR, pCDCAR1 CBWJC-0379 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ2319 Anti-BCAM (BRIC221) h(CD28-CD3ζ) CAR, pCDCAR1 Human BRIC221 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ2320 Anti-BCAM (CBWJC-0378) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBWJC-0378 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ2321 Anti-BCAM (CBWJC-0379) h(CD28-CD3ζ) CAR, pCDCAR1 CBWJC-0379 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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